In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cells.
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Variant base excision repair proteins: contributors to genomic instabilityUracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effectsDNA sequence analysis of spontaneous mutagenesis in Saccharomyces cerevisiaeO(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitionsThe maintenance of mitochondrial DNA integrity--critical analysis and updateTranscriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates.The large subunit of replication factor C (Rfc1p/Cdc44p) is required for DNA replication and DNA repair in Saccharomyces cerevisiae.DNA alkylation damage as a sensor of nitrosative stress in Mycobacterium tuberculosisGene expression profile and toxic effects in human bronchial epithelial cells exposed to zearalenonePurification and characterization of human 3-methyladenine-DNA glycosylaseIn vivo repair of methylation damage in Aag 3-methyladenine DNA glycosylase null mouse cellsRelease of normal bases from intact DNA by a native DNA repair enzyme.Overexpression of enzymes that repair endogenous damage to DNA.Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.Influence of S-adenosylmethionine pool size on spontaneous mutation, dam methylation, and cell growth of Escherichia coliImbalanced base excision repair increases spontaneous mutation and alkylation sensitivity in Escherichia coli.DNA damage to a single chromosome end delays anaphase onsetProficient repair in chromatin remodeling defective ino80 mutants of Saccharomyces cerevisiae highlights replication defects as the main contributor to DNA damage sensitivityThe adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.DNA repair mechanisms in dividing and non-dividing cells.Generation of a strong mutator phenotype in yeast by imbalanced base excision repair.Loss of Nfkb1 leads to early onset agingTrans-complementation by human apurinic endonuclease (Ape) of hypersensitivity to DNA damage and spontaneous mutator phenotype in apn1-yeast.Cloning of a 3-methyladenine-DNA glycosylase from Arabidopsis thalianaTumbling down a different pathway to genetic instability.Specificity of the mutator caused by deletion of the yeast structural gene (APN1) for the major apurinic endonuclease.DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coliMultiple isoforms of CDC25 oppose ATM activity to maintain cell proliferation during vertebrate development.Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteinsBalancing repair and tolerance of DNA damage caused by alkylating agentsMethylating agents and DNA repair responses: Methylated bases and sources of strand breaks.Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice.Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2'-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs.Three Brachypodium distachyon Uev1s Promote Ubc13-Mediated Lys63-Linked Polyubiquitination and Confer Different Functions.Depurination of N7-methylguanine by DNA glycosylase AlkD is dependent on the DNA backbone.Inflammasomes in Inflammation-Induced Cancer.Base excision repair intermediates as topoisomerase II poisons.The Pol beta-14 dominant negative rat DNA polymerase beta mutator mutant commits errors during the gap-filling step of base excision repair in Saccharomyces cerevisiae.
P2860
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P2860
In vivo evidence for endogenous DNA alkylation damage as a source of spontaneous mutation in eukaryotic cells.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
In vivo evidence for endogenou ...... mutation in eukaryotic cells.
@ast
In vivo evidence for endogenou ...... mutation in eukaryotic cells.
@en
type
label
In vivo evidence for endogenou ...... mutation in eukaryotic cells.
@ast
In vivo evidence for endogenou ...... mutation in eukaryotic cells.
@en
prefLabel
In vivo evidence for endogenou ...... mutation in eukaryotic cells.
@ast
In vivo evidence for endogenou ...... mutation in eukaryotic cells.
@en
P2860
P356
P1476
In vivo evidence for endogenou ...... mutation in eukaryotic cells.
@en
P2860
P304
P356
10.1073/PNAS.90.6.2117
P407
P577
1993-03-01T00:00:00Z