Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.
about
CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase.Characterization of magnesium requirement of human 5'-tyrosyl DNA phosphodiesterase mediated reactionInteraction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathwayTotal sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleasesDNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]APE1 incision activity at abasic sites in tandem repeat sequencesCockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediatesDynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and productEnhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatchThe inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis.Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human populationSubstitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.New insights into the structure of abasic DNA from molecular dynamics simulations.Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor.Functional characterization of Ape1 variants identified in the human populationBase excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1.A role for p53 in base excision repair.3'-phosphodiesterase activity of human apurinic/apyrimidinic endonuclease at DNA double-strand break endsRegulation of eukaryotic abasic endonucleases and their role in genetic stabilityMultiply damaged sites in DNA: interactions with Escherichia coli endonucleases III and VIIIElements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases.Interaction of the recombinant human methylpurine-DNA glycosylase (MPG protein) with oligodeoxyribonucleotides containing either hypoxanthine or abasic sites.Functional assessment of population and tumor-associated APE1 protein variantsJBP1 and JBP2 proteins are Fe2+/2-oxoglutarate-dependent dioxygenases regulating hydroxylation of thymidine residues in trypanosome DNAS-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.Characterization of the endoribonuclease active site of human apurinic/apyrimidinic endonuclease 1.Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions.Phosphotriester adducts (PTEs): DNA's overlooked lesion.Recognition of base J in duplex DNA by J-binding protein.Heat shock protein 70 binds to human apurinic/apyrimidinic endonuclease and stimulates endonuclease activity at abasic sites.Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.Thermodynamic, kinetic and structural basis for recognition and repair of abasic sites in DNA by apurinic/apyrimidinic endonuclease from human placenta.Reactivity of human apurinic/apyrimidinic endonuclease and Escherichia coli exonuclease III with bistranded abasic sites in DNA.Nm23-H1 protein binds to APE1 at AP sites and stimulates AP endonuclease activity following ionizing radiation of the human lung cancer A549 cells.Differences in replication of a DNA template containing an ethyl phosphotriester by T4 DNA polymerase and Escherichia coli DNA polymerase I.Role of active site tyrosines in dynamic aspects of DNA binding by AP endonuclease.The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sitesAP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair.
P2860
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P2860
Abasic site binding by the human apurinic endonuclease, Ape, and determination of the DNA contact sites.
description
1997 nî lūn-bûn
@nan
1997 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մարտին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Abasic site binding by the hum ...... tion of the DNA contact sites.
@ast
Abasic site binding by the hum ...... tion of the DNA contact sites.
@en
Abasic site binding by the hum ...... tion of the DNA contact sites.
@nl
type
label
Abasic site binding by the hum ...... tion of the DNA contact sites.
@ast
Abasic site binding by the hum ...... tion of the DNA contact sites.
@en
Abasic site binding by the hum ...... tion of the DNA contact sites.
@nl
prefLabel
Abasic site binding by the hum ...... tion of the DNA contact sites.
@ast
Abasic site binding by the hum ...... tion of the DNA contact sites.
@en
Abasic site binding by the hum ...... tion of the DNA contact sites.
@nl
P2093
P2860
P356
P1476
Abasic site binding by the hum ...... tion of the DNA contact sites.
@en
P2093
P2860
P304
P356
10.1093/NAR/25.5.933
P407
P577
1997-03-01T00:00:00Z