Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis
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AIP4/Itch regulates Notch receptor degradation in the absence of ligandBasal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motifNEMO recognition of ubiquitinated Bcl10 is required for T cell receptor-mediated NF-kappaB activationHemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1Ubiquitination-mediated regulation of interferon responsesStructural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.Disease-promoting effects of type I interferons in viral, bacterial, and coinfectionsA BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responsesRegulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligaseThe ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunityEndocytosis and signalling: intertwining molecular networksVpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.The SARS Coronavirus 3a protein causes endoplasmic reticulum stress and induces ligand-independent downregulation of the type 1 interferon receptor.Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptorMultiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor.Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferationQuality control for unfolded proteins at the plasma membrane.Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2Versatile roles of k63-linked ubiquitin chains in trafficking.Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway.Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptorWest Nile virus infection induces depletion of IFNAR1 protein levelsSuppressor of cytokine signaling (SOCS) 1 inhibits type I interferon (IFN) signaling via the interferon alpha receptor (IFNAR1)-associated tyrosine kinase Tyk2Vascular endothelial growth factor-induced elimination of the type 1 interferon receptor is required for efficient angiogenesisTyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor.Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFNα via accelerating the degradation of its receptorRegulation of antiviral innate immunity by deubiquitinase CYLD.Three lysine residues in the common β chain of the interleukin-5 receptor are required for Janus kinase (JAK)-dependent receptor ubiquitination, endocytosis, and signalingCurcumin inhibits interferon-γ signaling in colonic epithelial cells.The SnRK2-APC/C(TE) regulatory module mediates the antagonistic action of gibberellic acid and abscisic acid pathways.Activation of the JAK-STAT Signaling Pathway after In Vitro Stimulation with IFNß in Multiple Sclerosis Patients According to the Therapeutic Response to IFNß.Rabex-5 protein regulates the endocytic trafficking pathway of ubiquitinated neural cell adhesion molecule L1Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapiesLysine 48-linked polyubiquitination of organic anion transporter-1 is essential for its protein kinase C-regulated endocytosis.Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor.Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and ProgressionBoth K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor.Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway.Three ubiquitination sites of organic anion transporter-1 synergistically mediate protein kinase C-dependent endocytosis of the transporter.
P2860
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P2860
Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Site-specific ubiquitination e ...... ron-alpha receptor endocytosis
@ast
Site-specific ubiquitination e ...... ron-alpha receptor endocytosis
@en
type
label
Site-specific ubiquitination e ...... ron-alpha receptor endocytosis
@ast
Site-specific ubiquitination e ...... ron-alpha receptor endocytosis
@en
prefLabel
Site-specific ubiquitination e ...... ron-alpha receptor endocytosis
@ast
Site-specific ubiquitination e ...... ron-alpha receptor endocytosis
@en
P2093
P2860
P356
P1476
Site-specific ubiquitination e ...... ron-alpha receptor endocytosis
@en
P2093
Christopher J Carbone
Darren P Baker
Gayathri Swaminathan
Gergely L Lukacs
Hervé Barriere
Jianghuai Liu
Junmin Peng
K G Suresh Kumar
Serge Y Fuchs
P2860
P304
P356
10.1083/JCB.200706034
P407
P577
2007-12-01T00:00:00Z