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Protein stability promotes evolvabilitySynthetic promoter design for new microbial chassisEstablishing wild-type levels of catalytic activity on natural and artificial ( )8-barrel protein scaffoldsSelective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenaseExpanding the Nucleotide and Sugar 1-Phosphate Promiscuity of Nucleotidyltransferase RmlA via Directed EvolutionHIV-1 proviral DNA excision using an evolved recombinaseA general framework for thermodynamically consistent parameterization and efficient sampling of enzymatic reactionsBiocatalytic conversion of avermectin to 4''-oxo-avermectin: improvement of cytochrome p450 monooxygenase specificity by directed evolution.Investigating protein structural plasticity by surveying the consequence of an amino acid deletion from TEM-1 beta-lactamase.Computationally mapping sequence space to understand evolutionary protein engineering.Evolutionary fates within a microbial population highlight an essential role for protein folding during natural selection.A practical teaching course in directed protein evolution using the green fluorescent protein as a model.Advances in molecular engineering of carbohydrate-binding modules.Controlling enzyme inhibition using an expanded set of genetically encoded amino acids.Darwinian evolution on a chip.Engineering pH-tolerant mutants of a cyanide dihydratase.Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks.Directed evolution: an approach to engineer enzymes.Error-prone rolling circle amplification: the simplest random mutagenesis protocol.In vivo selection for the directed evolution of L-rhamnulose aldolase from L-rhamnulose-1-phosphate aldolase (RhaD).Selection and evolution of enzymes from a partially randomized non-catalytic scaffold.Mapping of protein-protein interaction sites by the 'absence of interference' approach.How protein stability and new functions trade offExpanded molecular diversity generation during directed evolution by trinucleotide exchange (TriNEx).High-throughput selection for cellulase catalysts using chemical complementation.Shedding light on the efficacy of laboratory evolution based on iterative saturation mutagenesis.TransCent: computational enzyme design by transferring active sites and considering constraints relevant for catalysis.Construction and flow cytometric screening of targeted enzyme libraries.Engineering next generation proteases.Simultaneous improvement of catalytic activity and thermal stability of tyrosine phenol-lyase by directed evolution.PCRless library mutagenesis via oligonucleotide recombination in yeastMetabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology.mRNA display for the selection and evolution of enzymes from in vitro-translated protein libraries.Manipulating the expression rate and enantioselectivity of an epoxide hydrolase by using directed evolution.A general strategy for the evolution of bond-forming enzymes using yeast displayA matching algorithm for catalytic residue site selection in computational enzyme design.Bacterial display in combinatorial protein engineering.A measure of the promiscuity of proteins and characteristics of residues in the vicinity of the catalytic site that regulate promiscuity.Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm.Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Evolving strategies for enzyme engineering.
@ast
Evolving strategies for enzyme engineering.
@en
type
label
Evolving strategies for enzyme engineering.
@ast
Evolving strategies for enzyme engineering.
@en
prefLabel
Evolving strategies for enzyme engineering.
@ast
Evolving strategies for enzyme engineering.
@en
P2093
P1476
Evolving strategies for enzyme engineering.
@en
P2093
Christopher R Otey
Derek MacMillan
Michelle M Meyer
Peter Meinhold
P304
P356
10.1016/J.SBI.2005.06.004
P577
2005-08-01T00:00:00Z