Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth. - Test2 - elhamkhani - TriplyDB

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

http://www.wikidata.org/entity/Q36191986

about

Mitochondrial disorders in children: toward development of small-molecule treatment strategies Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells Complex I inhibition augments dichloroacetate cytotoxicity through enhancing oxidative stress in VM-M3 glioblastoma cells.Altered expression of a metformin-mediated radiation response in SA-NH and FSa tumor cells treated under in vitro and in vivo growth conditions.Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.Inhibition of oxidative phosphorylation suppresses the development of osimertinib resistance in a preclinical model of EGFR-driven lung adenocarcinoma.The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration.The Mitochondrial Complex(I)ty of Cancer.Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma.The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells.Targeting Metabolism for Cancer Therapy.Super-enhancers define a proliferative PGC-1α-expressing melanoma subgroup sensitive to BET inhibition.AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization.Extracellular acidification induces ROS- and mPTP-mediated death in HEK293 cells.Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I.The Oncojanus Paradigm of Respiratory Complex I.Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification.Aspartate is an endogenous metabolic limitation for tumour growth Metabolic Profiles Associated With Metformin Efficacy in Cancer Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD

P2860

Q26767327-30461AAA-FD7D-41A6-8260-8F02E535F773 Q30844792-AC07BDC7-55DA-4679-AAF5-055D70A0284E Q38711927-2454CEA3-D734-4BFA-8B62-6707E4AEF8CC Q38712823-CB033E2B-3CF9-47CB-925B-276543C81C92 Q38740932-1A3A309C-32D0-40AB-BC6E-9597C8254EC9 Q38751306-695305D8-E8F6-4584-86D5-EF8217AAF8D0 Q39176363-2FE57804-9C0A-4266-BEBA-98C61C47AC73 Q39335352-43B8558C-D1BE-46D8-A3CF-B0276C2F4FC1 Q39392897-1691BB9E-DEDD-4E5D-8975-CB3892726556 Q42316246-AAA37B66-AF1A-4FD1-8EAC-B7EDED7B98E3 Q47232752-8889475A-242B-42A7-B6E4-D13F14AB0B49 Q47646742-262DD75E-8D00-446C-975C-06D594746CC8 Q47750108-935E8184-67B7-4F39-86A4-37522D6F2BE9 Q48022535-C9A240F3-AF87-4098-AEDD-C0A917A91E7B Q49458068-1758E5BC-C7D1-4082-A518-F09F0B1315A7 Q54969578-2BD4798C-8465-4B10-A4CE-C947E0BD0904 Q55114306-13D5D42D-5916-43CB-92C6-B850E70E409D Q55416886-52B89550-FD30-4A30-A138-187C8F4E0EF5 Q57095796-BA426B30-75B3-4E10-BE52-20953C61256B Q58728734-B86457A5-2ACF-40C5-8F88-8534A60630FC Q59132593-F5B2645F-C4B7-4104-85C6-FB8458FB41E1

P2860

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

http://www.wikidata.org/entity/Q36191986

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

@ast

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

@en

type

label

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

@ast

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

@en

prefLabel

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

@ast

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth.

@en

P1433

Q36191986-B7211361-43F2-44D7-8524-9160439C357D

P1476

Q36191986-D44F1BBA-856F-4A49-988B-9F4E956940DE

P2093

Q36191986-121FFC45-425E-4508-85A1-8F020B74C231

Q36191986-629BF967-CF73-4036-9B06-839C14BE1019

Q36191986-71886136-CA43-466B-B50E-1D6B61918049

Q36191986-9E1E02E3-96AC-4FE4-948D-6BDAB2064036

Q36191986-B529764A-CFF2-44DA-B848-98A858E779C6

Q36191986-CACBF043-5693-4AB8-BD73-CD911B388C00

Q36191986-F252D739-514B-425F-A19E-AAFB20AF3F6C

Q36191986-F84C5199-6E3F-438B-A67B-E980BA2308A4

Q36191986-FE82CF38-CE98-487A-AA51-0F7BD781C028

P2860

Q36191986-06A1DD03-F137-44E4-9480-8F78B2BC959E

Q36191986-109282D6-5ADD-4023-920B-A3AAEB120234

Q36191986-10B0B162-B5C8-4E63-8425-E42A4DBFAA1C

Q36191986-1348302D-E23B-48DC-ACBA-A53D67ABF939

Q36191986-16255120-3171-43F8-A7D1-A291B2AF6524

Q36191986-18542423-599B-4664-A90F-5B2AA8613134

Q36191986-1B8054BB-74DE-4FA9-90B3-4E7322A075A2

Q36191986-1BA01A05-7D95-4308-A161-4A196132693A

Q36191986-22673F6D-1CD1-48C8-9475-18C586105112

Q36191986-22B5AA3A-48E8-448E-BE37-6B16BF54F6C5

P2888

Q36191986-47A841F1-5B8D-478E-B417-87B4D14B9F39

P304

Q36191986-B884CF40-ADB0-4CDF-A917-02720188BFBD

P31

Q36191986-359520E4-03E2-4129-9F49-1DA99EC89B17

P356

Q36191986-97F945B5-DB5E-4BF2-A9E9-A0E6EB5F54F7

P478

Q36191986-5A5AE6C3-DF16-40C8-A7A5-D3C4944ADABE

P50

Q36191986-317173CB-A6F1-48FD-8FB9-A0C4DD3346DB

Q36191986-3B42884F-D8A7-4387-BF96-569AD163CDEB

Q36191986-E4FBEB28-354E-46E2-97BC-7C870AB524A5

P577

Q36191986-9E2BA952-E01B-4A55-B0A1-0C5C94408EE0

P5875

Q36191986-3E1DC263-1EEF-4F72-83DD-58AA4BB509F3

P6179

Q36191986-4C34147C-2BB8-4288-893D-001A3BF0F614

P698

Q36191986-50C06B62-F137-4923-818A-707AFD31C5F6

P932

Q36191986-01CF7BFE-88AD-4026-BC84-6764120CF282

P356

S40170-015-0138-0

P1433

Cancer & Metabolism

P1476

Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth

@en

P2093

Andrea Glasauer

http://www.w3.org/2001/XMLSchema#string

Andrea Hägebarth

http://www.w3.org/2001/XMLSchema#string

Carolyn Algire

http://www.w3.org/2001/XMLSchema#string

Charlotte Kopitz

http://www.w3.org/2001/XMLSchema#string

Farhan Basit

http://www.w3.org/2001/XMLSchema#string

Hoa Truong

http://www.w3.org/2001/XMLSchema#string

Katharina Bitschar

http://www.w3.org/2001/XMLSchema#string

Mélanie Héroult

http://www.w3.org/2001/XMLSchema#string

Werner Jh Koopman

http://www.w3.org/2001/XMLSchema#string

P2860

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

How mitochondria produce reactive oxygen species

Investigating metformin for cancer prevention and treatment: the end of the beginning

Glutamine and cancer: cell biology, physiology, and clinical opportunities

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

On the Origin of Cancer Cells

P2888

s40170-015-0138-0

P304

11

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1186/S40170-015-0138-0

http://www.w3.org/2001/XMLSchema#string

P478

3

http://www.w3.org/2001/XMLSchema#string

P50

Peter H Willems

Laura Schöckel

P577

2015-10-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

282776259

http://www.w3.org/2001/XMLSchema#string

P6179

1045060849

http://www.w3.org/2001/XMLSchema#string

P698

26500770

http://www.w3.org/2001/XMLSchema#string

P932

4615872

http://www.w3.org/2001/XMLSchema#string