The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens.
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Chronic Toxoplasma infection modifies the structure and the risk of host behaviorThe activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondiiThe gut mucosal immune response to Toxoplasma gondiiStriking the Right Balance Determines TB or Not TBThe IFN-γ-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity.The Toxoplasma pseudokinase ROP5 is an allosteric inhibitor of the immunity-related GTPases.Interferon-γ restricts Toxoplasma gondii development in murine skeletal muscle cells via nitric oxide production and immunity-related GTPases.Parasites paralyze cellular host defense system to promote virulence.The acute transcriptional response of the coral Acropora millepora to immune challenge: expression of GiMAP/IAN genes links the innate immune responses of corals with those of mammals and plants.Cytosolic phospholipase A(2)α and eicosanoids regulate expression of genes in macrophages involved in host defense and inflammation.Interferon γ-induced GTPase promotes invasion of Listeria monocytogenes into trophoblast giant cells.Innate responses to Toxoplasma gondii in mice and humansToxoplasma gondii effectors are master regulators of the inflammatory response.The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashionIFN-γ-induced macrophage antileishmanial mechanisms in mice: A role for immunity-related GTPases, Irgm1 and Irgm3, in Leishmania donovani infection in the liver.Lytic Cycle of Toxoplasma gondii: 15 Years Later.Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis.Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replicationA Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP.Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins.Repeated exposure to Lutzomyia intermedia sand fly saliva induces local expression of interferon-inducible genes both at the site of injection in mice and in human bloodToxoplasma gondii Inhibits gamma interferon (IFN-γ)- and IFN-β-induced host cell STAT1 transcriptional activity by increasing the association of STAT1 with DNA.Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii.Lipid droplet hijacking by intracellular pathogens.Ubiquitination of pathogen-containing vacuoles promotes host defense to Chlamydia trachomatis and Toxoplasma gondii.Mitochondria in innate immunity.Autophagy as an innate defense against mycobacteria.Interferon-inducible GTPases in cell autonomous and innate immunity.Irgm1 (LRG-47), a regulator of cell-autonomous immunity, does not localize to mycobacterial or listerial phagosomes in IFN-γ-induced mouse cells.Quo vadis? Interferon-inducible GTPases go to their target membranes via the LC3-conjugation system of autophagy.Experimental Porcine Toxoplasma gondii Infection as a Representative Model for Human Toxoplasmosis.Mice lack of LRG-47 display the attenuated outcome of infection with Schistosoma japonicum.Host-Toxoplasma gondii Coadaptation Leads to Fine Tuning of the Immune Response.Immune to defeat.The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.Mechanisms and functions of guanylate-binding proteins and related interferon-inducible GTPases: roles in intracellular lysis of pathogens.Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.T-bet-independent Th1 response induces intestinal immunopathology during Toxoplasma gondii infection.
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P2860
The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens.
description
2010 nî lūn-bûn
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2010年の論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年論文
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2010年论文
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2010年论文
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2010年论文
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name
The immunity-related GTPases i ...... ainst intracellular pathogens.
@ast
The immunity-related GTPases i ...... ainst intracellular pathogens.
@en
type
label
The immunity-related GTPases i ...... ainst intracellular pathogens.
@ast
The immunity-related GTPases i ...... ainst intracellular pathogens.
@en
prefLabel
The immunity-related GTPases i ...... ainst intracellular pathogens.
@ast
The immunity-related GTPases i ...... ainst intracellular pathogens.
@en
P2093
P2860
P1433
P1476
The immunity-related GTPases i ...... ainst intracellular pathogens.
@en
P2093
Carl G Feng
Julia P Hunn
P2860
P2888
P356
10.1007/S00335-010-9293-3
P577
2010-10-30T00:00:00Z