NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity - Test2 - elhamkhani - TriplyDB

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

http://www.wikidata.org/entity/Q36270944

about

Replication-Associated Recombinational Repair: Lessons from Budding Yeast Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease Targeting the kinase activities of ATR and ATM exhibits antitumoral activity in mouse models of MLL-rearranged AML.The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection Conditional mutation of Smc5 in mouse embryonic stem cells perturbs condensin localization and mitotic progression The (elusive) role of the SMC5/6 complex Efficacy of ATR inhibitors as single agents in Ewing sarcoma.Non-SMC Element 2 (NSMCE2) of the SMC5/6 Complex Helps to Resolve Topological Stress.SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.Nuclear Dynamics of Heterochromatin Repair.Functions of SUMO in the Maintenance of Genome Stability.Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6.POLD3 Is Haploinsufficient for DNA Replication in Mice.Smc5/6 Mediated Sumoylation of the Sgs1-Top3-Rmi1 Complex Promotes Removal of Recombination Intermediates.SENP2 suppresses epithelial-mesenchymal transition of bladder cancer cells through deSUMOylation of TGF-βRI.The Arabidopsis SUMO E3 ligase AtMMS21 dissociates the E2Fa/DPa complex in cell cycle regulation.SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements.

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P2860

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

http://www.wikidata.org/entity/Q36270944

description

2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

2015年學術文章

@zh

2015年學術文章

@zh-hant

name

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

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NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

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type

label

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

@ast

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

@en

prefLabel

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

@ast

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

@en

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The EMBO Journal

P1476

NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity

@en

P2093

Ariana Jacome

http://www.w3.org/2001/XMLSchema#string

Enrico Tenaglia

http://www.w3.org/2001/XMLSchema#string

Federica Schiavoni

http://www.w3.org/2001/XMLSchema#string

Matilde Murga

http://www.w3.org/2001/XMLSchema#string

Paula Gutierrez-Martinez

http://www.w3.org/2001/XMLSchema#string

Paula Martinez

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of a novel human SMC heterodimer homologous to the Schizosaccharomyces pombe Rad18/Spr18 complex

Human SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks

MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases

Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex

The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins

Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex

Repriming of DNA synthesis at stalled replication forks by human PrimPol

Human MMS21/NSE2 is a SUMO ligase required for DNA repair

Megabase chromatin domains involved in DNA double-strand breaks in vivo

Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions

P304

2604-2619

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scholarly article

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10.15252/EMBJ.201591829

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P433

21

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P478

34

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P50

Oscar Fernandez-Capetillo

Sara Rodriguez-Acebes

P577

2015-10-06T00:00:00Z

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283211167

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26443207

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4641528

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