Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).
about
Pseudokinases: update on their functions and evaluation as new drug targets.Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-bindingCbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction.Nucleotide-binding mechanisms in pseudokinases.JAK-STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects.Progress in understanding the safety and efficacy of Janus kinase inhibitors for treatment of rheumatoid arthritis.Genomic complexity and dynamics of clonal evolution in childhood acute myeloid leukemia studied with whole-exome sequencing.Mechanistic Insights into Regulation of JAK2 Tyrosine Kinase.Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders.
P2860
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P2860
Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2).
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Structural and Functional Char ...... mily Tyrosine Kinase 2 (TYK2).
@ast
Structural and Functional Char ...... mily Tyrosine Kinase 2 (TYK2).
@en
type
label
Structural and Functional Char ...... mily Tyrosine Kinase 2 (TYK2).
@ast
Structural and Functional Char ...... mily Tyrosine Kinase 2 (TYK2).
@en
prefLabel
Structural and Functional Char ...... mily Tyrosine Kinase 2 (TYK2).
@ast
Structural and Functional Char ...... mily Tyrosine Kinase 2 (TYK2).
@en
P2093
P2860
P356
P1476
Structural and Functional Char ...... mily Tyrosine Kinase 2 (TYK2).
@en
P2093
Brad Greenfield
Chris Gabel
Ellin-Kristina Hillert
John Eksterowicz
Merrill Ayres
Nigel Walker
Olli Silvennoinen
Sarah Maxwell
Steve Thibault
Xiaoshan Min
P2860
P304
27261-27270
P356
10.1074/JBC.M115.672048
P407
P577
2015-09-10T00:00:00Z