Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats.
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Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradationMechanisms of FUS mutations in familial amyotrophic lateral sclerosisOxidative stress and mitochondrial damage: importance in non-SOD1 ALSPathogenesis of FUS-associated ALS and FTD: insights from rodent modelsExpression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in ratsProfiling the genes affected by pathogenic TDP-43 in astrocytesAging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery.A single administration of human umbilical cord blood T cells produces long-lasting effects in the aging hippocampusA fruitful endeavor: modeling ALS in the fruit flyEvidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia.XBP1 depletion precedes ubiquitin aggregation and Golgi fragmentation in TDP-43 transgenic rats.Pathogenic mutation in VPS35 impairs its protection against MPP(+) cytotoxicityPathogenic Ubqln2 gains toxic properties to induce neuron death.Reactive astrocytes secrete lcn2 to promote neuron death.Changes in the Expression of FUS/TLS in Spinal Cords of SOD1 G93A Transgenic Mice and Correlation with Motor-Neuron Degeneration.The role of FUS gene variants in neurodegenerative diseases.AMPK Signalling and Defective Energy Metabolism in Amyotrophic Lateral Sclerosis.Targeting mitochondrial metal dyshomeostasis for the treatment of neurodegeneration.Advances in the Development of Disease-Modifying Treatments for Amyotrophic Lateral Sclerosis.The role of endoplasmic reticulum stress in neurodegenerative disease.Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons.ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.Mitochondrial quality control in amyotrophic lateral sclerosis: towards a common pathway?Increased Ubqln2 expression causes neuron death in transgenic ratsMitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice.Role and Therapeutic Potential of Astrocytes in Amyotrophic Lateral Sclerosis.Energy metabolism in ALS: an underappreciated opportunity?Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions.Amyotrophic Lateral Sclerosis associated FUS mutation shortens mitochondria and induces neurotoxicityNeurodegeneration-associated FUS is a novel regulator of circadian gene expressionFrom Mouse Models to Human Disease: An Approach for Amyotrophic Lateral Sclerosis
P2860
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P2860
Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Entorhinal cortical neurons ar ...... gation in FUS transgenic rats.
@ast
Entorhinal cortical neurons ar ...... gation in FUS transgenic rats.
@en
type
label
Entorhinal cortical neurons ar ...... gation in FUS transgenic rats.
@ast
Entorhinal cortical neurons ar ...... gation in FUS transgenic rats.
@en
prefLabel
Entorhinal cortical neurons ar ...... gation in FUS transgenic rats.
@ast
Entorhinal cortical neurons ar ...... gation in FUS transgenic rats.
@en
P2093
P2860
P356
P1476
Entorhinal cortical neurons ar ...... gation in FUS transgenic rats.
@en
P2093
Fangfang Bi
Hongxia Zhou
Jianbin Tong
Xu-Gang Xia
P2860
P304
P356
10.1093/HMG/DDS299
P577
2012-07-23T00:00:00Z