Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
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Treating brain tumors with PDE4 inhibitorsPrimary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengersProtein kinase A regulatory subunit distribution in medulloblastoma.Chemical modification of class II G protein-coupled receptor ligands: frontiers in the development of peptide analogs as neuroendocrine pharmacological therapiesPituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere culturesDiscovery of pituitary adenylate cyclase-activating polypeptide-regulated genes through microarray analyses in cell culture and in vivo.Expression analysis of PAC1-R and PACAP genes in zebrafish embryos.Neuropeptides shaping the central nervous system development: Spatiotemporal actions of VIP and PACAP through complementary signaling pathways.Pituitary adenylyl cyclase-activating peptide counteracts hedgehog-dependent motor neuron production in mouse embryonic stem cell cultures.Targeting brain tumor cAMP: the case for sex-specific therapeuticsSignaling through the neuropeptide GPCR PAC₁ induces neuritogenesis via a single linear cAMP- and ERK-dependent pathway using a novel cAMP sensor.Vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide, and their receptors and cancerThe G protein Gαs acts as a tumor suppressor in sonic hedgehog signaling-driven tumorigenesis.Pituitary adenylyl cyclase-activating polypeptide is an intrinsic regulator of Treg abundance and protects against experimental autoimmune encephalomyelitis.Interaction of PACAP with Sonic hedgehog reveals complex regulation of the hedgehog pathway by PKA.Perigestational dietary folic acid deficiency protects against medulloblastoma formation in a mouse model of nevoid basal cell carcinoma syndrome.Negative regulation of Hedgehog signaling by liver X receptors.G-protein-coupled receptors, Hedgehog signaling and primary cilia.Targeted treatment for sonic hedgehog-dependent medulloblastoma.Sonic hedgehog patterning during cerebellar development.Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation.Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.Distinct patterns of human medulloblastoma dissemination in the developing chick embryo nervous system.Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39.Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma.The complexities of G-protein-coupled receptor kinase function in Hedgehog signaling.Pleiotropic functions of pituitary adenylyl cyclase-activating polypeptide on retinal ontogenesis: involvement of KLF4 in the control of progenitor cell proliferation.
P2860
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P2860
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
@ast
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
@en
type
label
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
@ast
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
@en
prefLabel
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
@ast
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice.
@en
P2093
P2860
P1476
Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice
@en
P2093
Akop Seksenyan
Avegail Flores
Harley I Kornblum
Hiroko Nobuta
Hongmei Dong
James A Waschek
Joseph R Cohen
Linda M Liau
Matthew P Scott
Seririthanar Chhith
P2860
P304
P356
10.1016/J.YDBIO.2007.10.031
P407
P577
2007-11-26T00:00:00Z