An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma
about
Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrestDinosaurs and ancient civilizations: reflections on the treatment of cancerDerivation of high purity neuronal progenitors from human embryonic stem cellsStructure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation.Neoplasia: the second decade.INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumorsIdentification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors.Genomic profiling of plasmablastic lymphoma using array comparative genomic hybridization (aCGH): revealing significant overlapping genomic lesions with diffuse large B-cell lymphoma.The War on Cancer rages on.Physalin H from Solanum nigrum as an Hh signaling inhibitor blocks GLI1-DNA-complex formation.INSM1 increases N-myc stability and oncogenesis via a positive-feedback loop in neuroblastomaHh signaling inhibitors from Vitex negundo; naturally occurring inhibitors of the GLI1-DNA complex.Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.Insm1 promotes the transition of olfactory progenitors from apical and proliferative to basal, terminally dividing and neuronogenic.Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lipInsulinoma-associated 1: A novel nuclear marker in Merkel cell carcinoma (cutaneous neuroendocrine carcinoma).Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.Foxm1 controls a pro-stemness microRNA network in neural stem cells.Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.INSM1 Expression Is Frequent in Primary Central Nervous System Neoplasms but Not in the Adult Brain Parenchyma.
P2860
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P2860
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
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2008年學術文章
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name
An integrated approach identif ...... cerebellum and medulloblastoma
@ast
An integrated approach identif ...... cerebellum and medulloblastoma
@en
type
label
An integrated approach identif ...... cerebellum and medulloblastoma
@ast
An integrated approach identif ...... cerebellum and medulloblastoma
@en
prefLabel
An integrated approach identif ...... cerebellum and medulloblastoma
@ast
An integrated approach identif ...... cerebellum and medulloblastoma
@en
P2093
P2860
P50
P356
P1433
P1476
An integrated approach identif ...... cerebellum and medulloblastoma
@en
P2093
Alberto Gulino
Azzura Greco
Caterina Fragomeli
Concezio Di Rocco
Gianluca Canettieri
Isabella Screpanti
Lucia Di Marcotullio
Marella Maroder
Marianna Pelloni
Marta Moretti
P2860
P356
10.1593/NEO.07891
P577
2008-01-01T00:00:00Z