A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2.
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Research Advances on Pathways of Nickel-Induced ApoptosisThe Stability and Expression Level of Bok Are Governed by Binding to Inositol 1,4,5-Trisphosphate ReceptorsBH4 domain of Bcl-2 as a novel target for cancer therapyBCL2-BH4 antagonist BDA-366 suppresses human myeloma growth.A polysaccharide from Lentinus edodes inhibits human colon cancer cell proliferation and suppresses tumor growth in athymic nude mice.Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.Bcl-2 proteins and calcium signaling: complexity beneath the surface.Synergistic killing of human small cell lung cancer cells by the Bcl-2-inositol 1,4,5-trisphosphate receptor disruptor BIRD-2 and the BH3-mimetic ABT-263.Modulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum-Mitochondrial Interface.Regulation of Endoplasmic Reticulum-Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer TherapiesInvestigation of the neuroprotective effects of a novel synthetic compound via the mitochondrial pathway.Antagonizing Bcl-2's BH4 domain in cancer.Alterations in Ca2+ Signalling via ER-Mitochondria Contact Site Remodelling in Cancer.Multifunctional micelle delivery system for overcoming multidrug resistance of doxorubicin.Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax.Pathways and mechanisms of venetoclax resistance.Emerging molecular mechanisms in chemotherapy: Ca2+ signaling at the mitochondria-associated endoplasmic reticulum membranes.The mitochondrial pathway is involved in sodium fluoride (NaF)-induced renal apoptosis in miceExtracellular and ER-stored Ca contribute to BIRD-2-induced cell death in diffuse large B-cell lymphoma cellsBH4-mimetics and -antagonists: an emerging class of Bcl-2 protein modulators for cancer therapy
P2860
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P2860
A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
A synthetic peptide targeting ...... e BH3-binding pocket of Bcl-2.
@ast
A synthetic peptide targeting ...... e BH3-binding pocket of Bcl-2.
@en
type
label
A synthetic peptide targeting ...... e BH3-binding pocket of Bcl-2.
@ast
A synthetic peptide targeting ...... e BH3-binding pocket of Bcl-2.
@en
prefLabel
A synthetic peptide targeting ...... e BH3-binding pocket of Bcl-2.
@ast
A synthetic peptide targeting ...... e BH3-binding pocket of Bcl-2.
@en
P2093
P2860
P356
P1433
P1476
A synthetic peptide targeting ...... e BH3-binding pocket of Bcl-2.
@en
P2093
Andrew R Lavik
Clark W Distelhorst
Edward Greenberg
Frederic J Reu
Karen S McColl
Ming-Jin Chang
Mitchell R Smith
Shigemi Matsuyama
P2860
P304
27388-27402
P356
10.18632/ONCOTARGET.4489
P407
P577
2015-07-11T00:00:00Z