Embelin binds to human neuroserpin and impairs its polymerisation.

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Embelin binds to human neuroserpin and impairs its polymerisation.

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2016 nî lūn-bûn

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2016年の論文

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2016年学术文章

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2016年学术文章

@zh-cn

2016年学术文章

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2016年学术文章

@zh-my

2016年学术文章

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2016年學術文章

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2016年學術文章

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2016年學術文章

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Embelin binds to human neuroserpin and impairs its polymerisation.

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Embelin binds to human neuroserpin and impairs its polymerisation.

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Embelin binds to human neuroserpin and impairs its polymerisation.

@ast

Embelin binds to human neuroserpin and impairs its polymerisation.

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Embelin binds to human neuroserpin and impairs its polymerisation.

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Embelin binds to human neuroserpin and impairs its polymerisation.

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P1476

Embelin binds to human neuroserpin and impairs its polymerisation

@en

P2093

Claudia Moriconi

http://www.w3.org/2001/XMLSchema#string

Elena Miranda

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Fabio Sessa

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Giorgia Saga

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Michela Sala

http://www.w3.org/2001/XMLSchema#string

Rita Grandori

http://www.w3.org/2001/XMLSchema#string

Rosina Noto

http://www.w3.org/2001/XMLSchema#string

Samuele Raccosta

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P2860

Structure of a serpin-protease complex shows inhibition by deformation

Molecular basis of α1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer

Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates

Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

Human neuroserpin: structure and time-dependent inhibition

Familial dementia caused by polymerization of mutant neuroserpin

Mutant Neuroserpin (S49P) that causes familial encephalopathy with neuroserpin inclusion bodies is a poor proteinase inhibitor and readily forms polymers in vitro

Association between conformational mutations in neuroserpin and onset and severity of dementia

Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum

Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB

P2888

srep18769

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18769

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scholarly article

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10.1038/SREP18769

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English

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P50

P577

2016-01-06T00:00:00Z

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289521396

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P698

26732982

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P932

4702122

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