Navigating the protein fitness landscape with Gaussian processes
about
Chimeragenesis of distantly-related proteins by noncontiguous recombinationKey Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate BiasProteochemometric modeling in a Bayesian framework.Protein redesign by learning from data.Computationally designed libraries for rapid enzyme stabilization.SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution.Dissecting enzyme function with microfluidic-based deep mutational scanningActive machine learning-driven experimentation to determine compound effects on protein patterns.How Good Are Statistical Models at Approximating Complex Fitness Landscapes?Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Robust enzyme design: bioinformatic tools for improved protein stability.Global analysis of protein folding using massively parallel design, synthesis, and testing.Learning epistatic interactions from sequence-activity data to predict enantioselectivity.Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission.Machine learning to design integral membrane channelrhodopsins for efficient eukaryotic expression and plasma membrane localization.Application of fourier transform and proteochemometrics principles to protein engineeringProtein design: from computer models to artificial intelligencePredicting the evolution of Escherichia coli by a data-driven approach
P2860
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P2860
Navigating the protein fitness landscape with Gaussian processes
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
Navigating the protein fitness landscape with Gaussian processes
@ast
Navigating the protein fitness landscape with Gaussian processes
@en
type
label
Navigating the protein fitness landscape with Gaussian processes
@ast
Navigating the protein fitness landscape with Gaussian processes
@en
prefLabel
Navigating the protein fitness landscape with Gaussian processes
@ast
Navigating the protein fitness landscape with Gaussian processes
@en
P2860
P356
P1476
Navigating the protein fitness landscape with Gaussian processes
@en
P2093
Philip A Romero
P2860
P304
P356
10.1073/PNAS.1215251110
P407
P577
2012-12-31T00:00:00Z