Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. - Test2 - elhamkhani - TriplyDB

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.

http://www.wikidata.org/entity/Q36603910

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A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome p53 activation by knockdown technologies MRI reveals differential effects of amphetamine exposure on neuroglia in vivo Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors A computational study of off-target effects of RNA interference A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.Uncoupling of RNAi from active translation in mammalian cells.Small interfering RNAs containing full 2'-O-methylribonucleotide-modified sense strands display Argonaute2/eIF2C2-dependent activity.Transient and stable knockdown of the integrase cofactor LEDGF/p75 reveals its role in the replication cycle of human immunodeficiency virus The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16- or type 18-positive cervical cancer cell lines via translation reinitiation A novel biochemical method to identify target genes of individual microRNAs: identification of a new Caenorhabditis elegans let-7 target The promises and pitfalls of RNA-interference-based therapeutics RNA interference-based gene silencing as an efficient tool for functional genomics in hexaploid bread wheat Identification of antisense nucleic acid hybridization sites in mRNA molecules with self-quenching fluorescent reporter molecules Functional complementation of RNA interference mutants in trypanosomes Suppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels.Predicting and validating microRNA targets Short-term cytotoxic effects and long-term instability of RNAi delivered using lentiviral vectors HIV-1 resistance conferred by siRNA cosuppression of CXCR4 and CCR5 coreceptors by a bispecific lentiviral vector A rapid and sensitive assay for quantification of siRNA efficiency and specificity RNA interference by mixtures of siRNAs prepared using custom oligonucleotide arrays.CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection siRNA-mediated off-target gene silencing triggered by a 7 nt complementation (-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance.Thorough validation of siRNA-induced cell death phenotypes defines new anti-apoptotic protein siRNA Versus miRNA as Therapeutics for Gene Silencing Targeting γ-secretase in breast cancer Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II-dependent pathway in human K562 leukemia cells Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency Knockdown of Fcγ receptor III in an arthritic temporomandibular joint reduces the nociceptive response in rats Zscan4: a novel gene expressed exclusively in late 2-cell embryos and embryonic stem cells Polycystic kidney disease prevented by transgenic RNA interference Potential siRNA Molecules for Nucleoprotein and M2/L Overlapping Region of Respiratory Syncytial Virus: In Silico Design Notch inhibition as a promising new approach to cancer therapy.Generation of an external guide sequence library for a reverse genetic screen in Caenorhabditis elegans.

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Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.

http://www.wikidata.org/entity/Q36603910

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2004 nî lūn-bûn

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Short interfering RNAs can ind ...... d proteins in mammalian cells.

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Proceedings of the National Academy of Sciences of the United States of America

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Short interfering RNAs can ind ...... d proteins in mammalian cells.

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Arindam Bhattacharjee

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Christina M Hughes

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Jeffrey C Lee

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Kalai Selvi Shanmugam

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Lowell Umayam

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Peter C Scacheri

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Tyra G Wolfsberg

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P2860

Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling

Menin, a gene product responsible for multiple endocrine neoplasia type 1, interacts with the putative tumor metastasis suppressor nm23

Menin interacts directly with the homeobox-containing protein Pem

The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation

Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain

Menin, the product of the MEN1 gene, is a nuclear protein

The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene

New microRNAs from mouse and human

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

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101

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Francis Collins

Matthew Meyerson

Natasha J. Caplen

Orit Rozenblatt-Rosen

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2004-02-09T00:00:00Z

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7221793

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14769924

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357023

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