Variations in the FTO gene are associated with severe obesity in the Japanese
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The bigger picture of FTO: the first GWAS-identified obesity geneA preliminary association study of fat mass and obesity associated gene polymorphisms and degenerative disc disease in a Chinese Han populationAssessing gene-treatment interactions at the FTO and INSIG2 loci on obesity-related traits in the Diabetes Prevention Program.Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes.The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924.Prevalence of loss-of-function FTO mutations in lean and obese individualsAssociation of genetic polymorphism of PPARĪ³-2, ACE, MTHFR, FABP-2 and FTO genes in risk prediction of type 2 diabetes mellitusRisk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study.Recent progress in the genetics of common obesityThe common rs9939609 variant of the fat mass and obesity-associated gene is associated with obesity risk in children and adolescents of Beijing, China.Variant rs9939609 in the FTO gene is associated with body mass index among Chinese childrenAssociations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk.The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice.Genetic association of FTO/IRX region with obesity and overweight in the Polish population.Detailed analysis of variants in FTO in association with body composition in a cohort of 70-year-olds suggests a weakened effect among elderly.FTO gene polymorphisms and obesity risk: a meta-analysis.Common genetic variants and central adiposity among Asian-Indians.The genetics of obesity: FTO leads the way.The effects of genetic variation in FTO rs9939609 on obesity and dietary preferences in Chinese Han children and adolescents.Evaluation of genetic susceptibility loci for obesity in Chinese women.Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.The fat mass and obesity associated gene, FTO, is also associated with osteoporosis phenotypesDetermination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children.Rs7206790 and rs11644943 in FTO gene are associated with risk of obesity in Chinese school-age population.Current review of genetics of human obesity: from molecular mechanisms to an evolutionary perspective.Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis.Association of FTO polymorphisms with obesity and obesity-related outcomes in Portuguese childrenContribution of common genetic variants to obesity and obesity-related traits in mexican children and adults.Genetic Effects of FTO and MC4R Polymorphisms on Body Mass in Constitutional Types.An FTO variant is associated with Type 2 diabetes in South Asian populations after accounting for body mass index and waist circumferenceAssociation between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.Involvement of leptin receptor long isoform (LepRb)-STAT3 signaling pathway in brain fat mass- and obesity-associated (FTO) downregulation during energy restriction.Genetics of Obesity: What have we Learned?Dietary Fat Modifies the Effects of FTO Genotype on Changes in Insulin Sensitivity.Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations.Mixture SNPs effect on phenotype in genome-wide association studies.A high intake of saturated fatty acids strengthens the association between the fat mass and obesity-associated gene and BMI.Education modulates the association of the FTO rs9939609 polymorphism with body mass index and obesity risk in the Mediterranean population.Interactions between the FTO rs9939609 polymorphism, body mass index, and lifestyle-related factors on metabolic syndrome risk.FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More?
P2860
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P2860
Variations in the FTO gene are associated with severe obesity in the Japanese
description
2008 nĆ® lÅ«n-bĆ»n
@nan
2008幓ć®č«ę
@ja
2008幓č«ę
@yue
2008幓č«ę
@zh-hant
2008幓č«ę
@zh-hk
2008幓č«ę
@zh-mo
2008幓č«ę
@zh-tw
2008幓č®ŗę
@wuu
2008幓č®ŗę
@zh
2008幓č®ŗę
@zh-cn
name
Variations in the FTO gene are associated with severe obesity in the Japanese
@ast
Variations in the FTO gene are associated with severe obesity in the Japanese
@en
type
label
Variations in the FTO gene are associated with severe obesity in the Japanese
@ast
Variations in the FTO gene are associated with severe obesity in the Japanese
@en
prefLabel
Variations in the FTO gene are associated with severe obesity in the Japanese
@ast
Variations in the FTO gene are associated with severe obesity in the Japanese
@en
P2093
P2860
P1476
Variations in the FTO gene are associated with severe obesity in the Japanese
@en
P2093
Atsushi Nakajima
Hiroaki Masuzaki
Hironobu Yoshimatsu
Ikuo Mineo
Katsuto Tokunaga
Kazuaki Kotani
Kazuwa Nakao
Kazuyuki Hamaguchi
Kentaro Yamada
P2860
P2888
P304
P356
10.1007/S10038-008-0283-1
P577
2008-04-01T00:00:00Z