Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT). - Test2 - elhamkhani - TriplyDB

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

http://www.wikidata.org/entity/Q36732669

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CTCF binds the proximal exonic region of hTERT and inhibits its transcription.Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression Broad targeting of angiogenesis for cancer prevention and therapy Effect of connective tissue growth factor on hypoxia-inducible factor 1alpha degradation and tumor angiogenesis The hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironment Hypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model.Hypoxia reoxygenation induces premature senescence in neonatal SD rat cardiomyocytes.Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia.The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans.RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1alpha as critical for telomerase function in murine embryonic stem cells Soliciting strategies for developing cell-based reference materials to advance mesenchymal stromal cell research and clinical translation.TERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.Purification and identification of a transcription factor, USF-2, binding to E-box element in the promoter of human telomerase reverse transcriptase (hTERT).RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growth Telomeres and immunological diseases of aging Microenvironmental regulation of telomerase isoforms in human embryonic stem cells Increased placental telomerase mRNA in hypertensive disorders of pregnancy Hypoxia-inducible factors, stem cells, and cancer Genome-wide identification and annotation of HIF-1α binding sites in two cell lines using massively parallel sequencing.Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene.Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma.Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia Stroma targeting nuclear imaging and radiopharmaceuticals.Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.The Role of Hypoxia and Cancer Stem Cells in Renal Cell Carcinoma Pathogenesis.The long and short of it: the role of telomeres in fetal origins of adult disease.Upstream stimulatory factor 2 and hypoxia-inducible factor 2α (HIF2α) cooperatively activate HIF2 target genes during hypoxia.Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptors Development of novel therapeutic strategies that target HIF-1.Telomerase activity in pregnancy complications (Review).Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer TERT alleviates irradiation-induced late rectal injury by reducing hypoxia-induced ROS levels through the activation of NF-κB and autophagy.Placental pseudo-malignancy from a DNA methylation perspective: unanswered questions and future directions.Hypoxia and senescence: the impact of oxygenation on tumor suppression Human telomerase expression regulation.Age related cardiovascular dysfunction and effects of physical activity.The growing complexity of HIF-1α's role in tumorigenesis: DNA repair and beyond.Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.

P2860

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P2860

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

http://www.wikidata.org/entity/Q36732669

description

2004 nî lūn-bûn

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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2004年论文

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2004年论文

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name

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

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Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

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type

label

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

@ast

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

@en

prefLabel

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

@ast

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

@en

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MCB.24.13.6076-6083.2004

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Molecular and Cellular Biology

P1476

Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT).

@en

P2093

Hirotaka Nishi

http://www.w3.org/2001/XMLSchema#string

Jerry W Shay

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Keiichi Isaka

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Masaki Inoue

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Satoru Kyo

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Toshihide Nakada

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P2860

Hypoxia extends the life span of vascular smooth muscle cells through telomerase activation.

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

Specific association of human telomerase activity with immortal cells and cancer

HIF-1 and human disease: one highly involved factor

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

Developmental regulation of the expression of 72 and 92 kd type IV collagenases in human trophoblasts: a possible mechanism for control of trophoblast invasion

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

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