Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers - Test2 - elhamkhani - TriplyDB

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

http://www.wikidata.org/entity/Q25255387

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A breast cancer prognostic signature predicts clinical outcomes in multiple tumor types Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor HSulf-1 modulates FGF2- and hypoxia-mediated migration and invasion of breast cancer cells SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer Breast cancer in the personal genomics era Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation.Big Data Analytics for Prostate Radiotherapy Hypoxia and Hypoxia-Inducible Factors in Leukemias REST is a hypoxia-responsive transcriptional repressor Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA Comprehensive analysis of glycolytic enzymes as therapeutic targets in the treatment of glioblastoma 'Omic approaches to preventing or managing metastatic breast cancer A simple but highly effective approach to evaluate the prognostic performance of gene expression signatures miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors Nrf2 is the key to chemotherapy resistance in MCF7 breast cancer cells under hypoxia Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes A concerted HIF-1α/MT1-MMP signalling axis regulates the expression of the 3BP2 adaptor protein in hypoxic mesenchymal stromal cells Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia.Breaking through a plateau in renal cell carcinoma therapeutics: development and incorporation of biomarkers FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data.An 18-gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer Use of culture geometry to control hypoxia-induced vascular endothelial growth factor secretion from adipose-derived stem cells: optimizing a cell-based approach to drive vascular growth Cancer diagnosis marker extraction for soft tissue sarcomas based on gene expression profiling data by using projective adaptive resonance theory (PART) filtering method.Warburg effect's manifestation in aggressive pheochromocytomas and paragangliomas: insights from a mouse cell model applied to human tumor tissue.Acquisition of biologically relevant gene expression data by Affymetrix microarray analysis of archival formalin-fixed paraffin-embedded tumours Gene expression programs of human smooth muscle cells: tissue-specific differentiation and prognostic significance in breast cancers.Modeling cancer progression via pathway dependencies The removal of multiplicative, systematic bias allows integration of breast cancer gene expression datasets - improving meta-analysis and prediction of prognosis.Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers.The genomic analysis of lactic acidosis and acidosis response in human cancers Massive transcriptional start site analysis of human genes in hypoxia cells.A compact VEGF signature associated with distant metastases and poor outcomes.STAT1 pathway mediates amplification of metastatic potential and resistance to therapy Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.The l1-l2 regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines.Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models.IGF-I induced genes in stromal fibroblasts predict the clinical outcome of breast and lung cancer patients.Modelling p-value distributions to improve theme-driven survival analysis of cancer transcriptome datasets.Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones

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P2860

Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers

http://www.wikidata.org/entity/Q25255387

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2006 nî lūn-bûn

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Ali Salim

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Amato Giaccia

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Michael T Longaker

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Yun Wang

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Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds

Involvement of chemokine receptors in breast cancer metastasis

Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

Significance analysis of microarrays applied to the ionizing radiation response

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

Cluster analysis and display of genome-wide expression patterns

Inhibition of HIF2alpha is sufficient to suppress pVHL-defective tumor growth

A gene-expression program reflecting the innate immune response of cultured intestinal epithelial cells to infection by Listeria monocytogenes

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

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Anne-Lise Børresen-Dale

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