MLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors.
about
Targeting the overexpressed ROC1 induces G2 cell cycle arrest and apoptosis in esophageal cancer cellsTargeting prohibitins induces apoptosis in acute myeloid leukemia cells.Rational combination strategies to enhance venetoclax activity and overcome resistance in hematologic malignancies.Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1.Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor.Selective targeting of BCL6 induces oncogene addiction switching to BCL2 in B-cell lymphomaMLN4924 suppresses neddylation and induces cell cycle arrest, senescence, and apoptosis in human osteosarcomaAssessment of Drug Sensitivity in Hematopoietic Stem and Progenitor Cells from Acute Myelogenous Leukemia and Myelodysplastic Syndrome Ex Vivo.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.Measurement of BH3-only protein tolerance.Pevonedistat, a first-in-class NEDD8-activating enzyme (NAE) inhibitor, combined with azacitidine, in patients with AML.Protein neddylation and its alterations in human cancers for targeted therapy.Pathways and mechanisms of venetoclax resistance.
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P2860
MLN4924 induces Noxa upregulation in acute myelogenous leukemia and synergizes with Bcl-2 inhibitors.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
MLN4924 induces Noxa upregulat ...... ergizes with Bcl-2 inhibitors.
@en
type
label
MLN4924 induces Noxa upregulat ...... ergizes with Bcl-2 inhibitors.
@en
prefLabel
MLN4924 induces Noxa upregulat ...... ergizes with Bcl-2 inhibitors.
@en
P2093
P2860
P356
P1476
MLN4924 induces Noxa upregulat ...... nergizes with Bcl-2 inhibitors
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2015.74
P577
2015-06-05T00:00:00Z