about
Proteoglycan form and function: A comprehensive nomenclature of proteoglycansDecorin causes autophagy in endothelial cells via Peg3Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cellsOncosuppressive functions of decorinAntiangiogenic mechanisms and factors in breast cancer treatmentExtracellular matrix macromolecules: potential tools and targets in cancer gene therapyPivotal role for decorin in angiogenesisInsights into the key roles of proteoglycans in breast cancer biology and translational medicineSignaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21Expression analysis of human pterygium shows a predominance of conjunctival and limbal markers and genes associated with cell migration.Cytogenetic and cDNA microarray expression analysis of MCF10 human breast cancer progression cell lines.Decorin deficiency promotes hepatic carcinogenesisExtracellular matrix molecules: potential targets in pharmacotherapy.Recombinant fibromodulin and decorin effects on NF-κB and TGFβ1 in the 4T1 breast cancer cell line.Differential expression of decorin, EGFR and cyclin D1 during mammary gland carcinogenesis in TA2 mice with spontaneous breast cancerThe expression of syndecan-1, syndecan-4 and decorin in healthy human breast tissue during the menstrual cycle.Mitostatin is down-regulated in human prostate cancer and suppresses the invasive phenotype of prostate cancer cellsIntegrated proteomic, transcriptomic, and biological network analysis of breast carcinoma reveals molecular features of tumorigenesis and clinical relapseProgesterone--promoter or inhibitor of breast cancer.Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycansTarget-seeking antifibrotic compound enhances wound healing and suppresses scar formation in mice.Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft modelDecorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesisPeriostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion.Microdialysis combined with proteomics for protein identification in breast tumor microenvironment in vivo.The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer.Decorin antagonizes IGF receptor I (IGF-IR) function by interfering with IGF-IR activity and attenuating downstream signaling.Decorin-mediated inhibition of colorectal cancer growth and migration is associated with E-cadherin in vitro and in miceDecorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.ASPN and GJB2 Are Implicated in the Mechanisms of Invasion of Ductal Breast CarcinomasDecorin: a guardian from the matrixLocalization of decorin gene expression in normal human breast tissue and in benign and malignant tumors of the human breast.Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancerDecorin as a multivalent therapeutic agent against cancer.Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy.Proteoglycans in cancer biology, tumour microenvironment and angiogenesis.Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.Dichotomy of decorin activity on the insulin-like growth factor-I systemDecorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis.
P2860
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P2860
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
An antimetastatic role for decorin in breast cancer.
@en
type
label
An antimetastatic role for decorin in breast cancer.
@en
prefLabel
An antimetastatic role for decorin in breast cancer.
@en
P2093
P2860
P1476
An antimetastatic role for decorin in breast cancer
@en
P2093
Daniela G Seidler
David J McQuillan
Jack Heath
Mathew L Thakur
Raffaele Baffa
Rick T Owens
Silvia Goldoni
P2860
P304
P356
10.2353/AJPATH.2008.080275
P407
P577
2008-08-07T00:00:00Z