Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.
about
Proteoglycan form and function: A comprehensive nomenclature of proteoglycansDecorin causes autophagy in endothelial cells via Peg3Lumican: a new inhibitor of matrix metalloproteinase-14 activityDecorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cellsOncosuppressive functions of decorinDecorin: A Growth Factor Antagonist for Tumor Growth InhibitionDecoding the Matrix: Instructive Roles of Proteoglycan ReceptorsBiological interplay between proteoglycans and their innate immune receptors in inflammationExtracellular Matrix, a Hard Player in AngiogenesisPivotal role for decorin in angiogenesisInsights into the key roles of proteoglycans in breast cancer biology and translational medicineOpticin exerts its anti-angiogenic activity by regulating extracellular matrix adhesivenessDecorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin.Fibromodulin promoted in vitro and in vivo angiogenesisBiglycan and decorin differentially regulate signaling in the fetal membranesDecorin differentially modulates the activity of insulin receptor isoform A ligands.Decorin deficiency promotes hepatic carcinogenesisKey roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiologyPrinciples of liver regeneration and growth homeostasis.Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft modelPeriostin suppression induces decorin secretion leading to reduced breast cancer cell motility and invasion.Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes.The systemic delivery of an oncolytic adenovirus expressing decorin inhibits bone metastasis in a mouse model of human prostate cancer.Possible dual role of decorin in abdominal aortic aneurysm.Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation.Inhibition of Pediatric Glioblastoma Tumor Growth by the Anti-Cancer Agent OKN-007 in Orthotopic Mouse Xenografts.Higher Decorin Levels in Bone Marrow Plasma Are Associated with Superior Treatment Response to Novel Agent-Based Induction in Patients with Newly Diagnosed Myeloma - A Retrospective Study.Restoration of mesenchymal retinal pigmented epithelial cells by TGFβ pathway inhibitors: implications for age-related macular degenerationDecorin: a guardian from the matrixDecorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagySystemic Delivery of an Oncolytic Adenovirus Expressing Decorin for the Treatment of Breast Cancer Bone MetastasesLocalization of decorin gene expression in normal human breast tissue and in benign and malignant tumors of the human breast.Decorin as a multivalent therapeutic agent against cancer.Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.Dichotomy of decorin activity on the insulin-like growth factor-I systemMechanisms of trophoblast migration, endometrial angiogenesis in preeclampsia: The role of decorin.Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept.Matricellular proteins as regulators of cancer metastasis to bone.Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.Biological functions of decorin in cancer.
P2860
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P2860
Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Decorin antagonizes the angiog ...... of thrombospondin-1 and TIMP3.
@ast
Decorin antagonizes the angiog ...... of thrombospondin-1 and TIMP3.
@en
type
label
Decorin antagonizes the angiog ...... of thrombospondin-1 and TIMP3.
@ast
Decorin antagonizes the angiog ...... of thrombospondin-1 and TIMP3.
@en
prefLabel
Decorin antagonizes the angiog ...... of thrombospondin-1 and TIMP3.
@ast
Decorin antagonizes the angiog ...... of thrombospondin-1 and TIMP3.
@en
P2093
P2860
P50
P356
P1476
Decorin antagonizes the angiog ...... of thrombospondin-1 and TIMP3
@en
P2093
Michael P Lisanti
Rick T Owens
Simone Buraschi
Thomas Neill
P2860
P304
P356
10.1074/JBC.M111.283499
P407
P577
2011-12-22T00:00:00Z