Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.
about
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunityImmunoregulatory functions of immune complexes in vaccine and therapyTRIM21: a cytosolic Fc receptor with broad antibody isotype specificityFc receptors and their influence on efficacy of therapeutic antibodies for treatment of viral diseasesB in TB: B Cells as Mediators of Clinically Relevant Immune Responses in TuberculosisThe cytoskeleton in cell-autonomous immunity: structural determinants of host defenceCellular self-defense: how cell-autonomous immunity protects against pathogensAntibodies and tuberculosisCoordinated Neutralization and Immune Activation by the Cytosolic Antibody Receptor TRIM21Gene expression profiling of the response to interferon beta in Epstein-Barr-transformed and primary B cells of patients with multiple sclerosisImmune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic CellsNon-neutralizing antibodies induced by seasonal influenza vaccine prevent, not exacerbate A(H1N1)pdm09 disease.Polarized cell migration during cell-to-cell transmission of herpes simplex virus in human skin keratinocytes.PKA-dependent dynein switching from lysosomes to adenovirus: a novel form of host-virus competition.A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesisContribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal StudiesOral retinyl palmitate or retinoic acid corrects mucosal IgA responses toward an intranasal influenza virus vaccine in vitamin A deficient mice.FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection.Role of Fc in antibody-mediated protection from ricin toxinEnhancement of Th1/Th17 inflammation by TRIM21 in Behçet's disease.Antiviral Functions of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific IgG Antibodies: Effects of Antiretroviral Therapy and Implications for Therapeutic HIV-1 Vaccine Design.TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles.The long elusive IgM Fc receptor, FcμR.Translocalized IgA mediates neutralization and stimulates innate immunity inside infected cells.Intracellular sensing of complement C3 activates cell autonomous immunity.Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogensIgG subclasses and allotypes: from structure to effector functions.A dual character of flavonoids in influenza A virus replication and spread through modulating cell-autonomous immunity by MAPK signaling pathways.Genetics of transfusion recipient alloimmunization: can clues from susceptibility to autoimmunity pave the way?TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systemsHuman CD8+ T-cells recognizing peptides from Mycobacterium tuberculosis (Mtb) presented by HLA-E have an unorthodox Th2-like, multifunctional, Mtb inhibitory phenotype and represent a novel human T-cell subset.Role of microRNA modulation in the interferon-α/ribavirin suppression of HIV-1 in vivoA re-evaluation of the role of B cells in protective immunity to Chlamydia infectionTRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus.RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.Delicate coordination of TRIM21's dual activity in virus neutralization and signaling.Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21TRIM5α requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription.Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful TreatmentcDNA phage display for the discovery of theranostic autoantibodies in rheumatoid arthritis.
P2860
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P2860
Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Intracellular antibody-bound p ...... ng via the Fc receptor TRIM21.
@en
type
label
Intracellular antibody-bound p ...... ng via the Fc receptor TRIM21.
@en
prefLabel
Intracellular antibody-bound p ...... ng via the Fc receptor TRIM21.
@en
P2860
P50
P356
P1433
P1476
Intracellular antibody-bound p ...... ng via the Fc receptor TRIM21.
@en
P2093
Donna L Mallery
Leo C James
P2860
P304
P356
10.1038/NI.2548
P407
P577
2013-03-03T00:00:00Z