Metformin: do we finally have an anti-aging drug? - Test2 - elhamkhani - TriplyDB

Metformin: do we finally have an anti-aging drug?

Metformin: do we finally have an anti-aging drug?

http://www.wikidata.org/entity/Q37530252

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Repurposing metformin: an old drug with new tricks in its binding pockets Epigenetics and aging Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging Molecules New insights into the role of mitochondrial dynamics and autophagy during oxidative stress and aging in the heart Lifespan extension and cancer prevention in HER-2/neu transgenic mice treated with low intermittent doses of rapamycin The anti-aging effects of LW-AFC via correcting immune dysfunctions in senescence accelerated mouse resistant 1 (SAMR1) strain Do metformin a real anticarcinogen? A critical reappraisal of experimental data.Latest progress in tyrosine kinase inhibitors Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): study protocol for a randomized controlled trial.From rapalogs to anti-aging formula.In search of antiaging modalities: evaluation of mTOR- and ROS/DNA damage-signaling by cytometry.Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin.Impacts of metformin and aspirin on life history features and longevity of crickets: trade-offs versus cost-free life extension?Comparison of rapamycin schedules in mice on high-fat diet.Koschei the immortal and anti-aging drugs Different effect of testosterone and oestrogen on urinary excretion of metformin via regulating OCTs and MATEs expression in the kidney of mice.The cell-autonomous mechanisms underlying the activity of metformin as an anticancer drug Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging.Insulin resistance in the liver: deficiency or excess of insulin?The dog aging project: translational geroscience in companion animals.Nutritional strategies to optimise cognitive function in the aging brain.Metformin: New Preparations and Nonglycemic Benefits.Metformin targets histone acetylation in cancer-prone epithelial cells.Quantitative and Systems Pharmacology 3. Network-Based Identification of New Targets for Natural Products Enables Potential Uses in Aging-Associated Disorders.Geroprotectors as a therapeutic strategy for COPD - where are we now?Metformin Potentiates the Benefits of Dietary Restraint: A Metabolomic Study.60 years of metformin use: a glance at the past and a look to the future.Targeting glucose metabolism for healthy aging.prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells Metformin: An Old Drug with New Applications

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Metformin: do we finally have an anti-aging drug?

http://www.wikidata.org/entity/Q37530252

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 October 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Metformin: do we finally have an anti-aging drug?

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Metformin: do we finally have an anti-aging drug?

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Metformin: do we finally have an anti-aging drug?

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Metformin: do we finally have an anti-aging drug?

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Metformin: do we finally have an anti-aging drug?

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Metformin: do we finally have an anti-aging drug?

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Metformin: do we finally have an anti-aging drug?

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Vladimir N Anisimov

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Role of AMP-activated protein kinase in mechanism of metformin action

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

mTOR is a key modulator of ageing and age-related disease

The hallmarks of aging

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila

The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

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3483-3489

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