Coordinate regulation of G- and C strand length during new telomere synthesis.
about
Human telomerase contains two cooperating telomerase RNA molecules.Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2Structure and function of the telomeric CST complexThe Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 proteinThe role of Stn1p in Saccharomyces cerevisiae telomere capping can be separated from its interaction with Cdc13p.Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.Thermodynamic characterization of binding Oxytricha nova single strand telomere DNA with the alpha protein N-terminal domain.Natural and pharmacological regulation of telomeraseAlterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha.Mcl1p is a polymerase alpha replication accessory factor important for S-phase DNA damage survival.The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis.Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres.De novo telomere addition to spacer sequences prior to their developmental degradation in Euplotes crassus.mcl1+, the Schizosaccharomyces pombe homologue of CTF4, is important for chromosome replication, cohesion, and segregation.Interactions between telomerase and primase physically link the telomere and chromosome replication machinery.Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in ArabidopsisTelomerase in the human organism.Conserved DNA sequences adjacent to chromosome fragmentation and telomere addition sites in Euplotes crassus.Replication proteins influence the maintenance of telomere length and telomerase protein stabilityDevelopmentally programmed assembly of higher order telomerase complexes with distinct biochemical and structural properties.Telomere end processing: unexpected complexity at the end game.Replication and protection of telomeres.Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance.Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase.Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells.Rap1 binds single-stranded DNA at telomeric double- and single-stranded junctions and competes with Cdc13 protein.Multiple four-stranded conformations of human telomere sequence d(CCCTAA) in solution.In vitro expansion of mammalian telomere repeats by DNA polymerase alpha-primase.Mapping the FEN1 interaction domain with hTERT.Cdc13 both positively and negatively regulates telomere replication.Rap1 and Cdc13 have complementary roles in preventing exonucleolytic degradation of telomere 5' endsDysfunction of chromatin assembly factor 1 induces shortening of telomeres and loss of 45S rDNA in Arabidopsis thaliana.Sequential phosphorylation of CST subunits by different cyclin-Cdk1 complexes orchestrate telomere replication.
P2860
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P2860
Coordinate regulation of G- and C strand length during new telomere synthesis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Coordinate regulation of G- and C strand length during new telomere synthesis.
@en
type
label
Coordinate regulation of G- and C strand length during new telomere synthesis.
@en
prefLabel
Coordinate regulation of G- and C strand length during new telomere synthesis.
@en
P2860
P356
P1476
Coordinate regulation of G- and C strand length during new telomere synthesis.
@en
P2860
P304
P356
10.1091/MBC.8.11.2145
P577
1997-11-01T00:00:00Z