Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome.
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Evolution in health and medicine Sackler colloquium: Comparative genomics of autism and schizophreniaGroup 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and diseaseA new look at an old drug: neuroprotective effects and therapeutic potentials of lithium saltsDysregulation and restoration of translational homeostasis in fragile X syndromeAstrocytes conspire with neurons during progression of neurological diseaseMatrix metalloproteinases and minocycline: therapeutic avenues for fragile X syndrome.The function of RNA-binding proteins at the synapse: implications for neurodegenerationDendritic spine dysgenesis in autism related disordersRepeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disordersTargeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromesLTD-like molecular pathways in developmental synaptic pruningNanomolar bifenthrin alters synchronous Ca2+ oscillations and cortical neuron development independent of sodium channel activityIncreased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarkerOpposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine DensityIdentification and characterisation of Simiate, a novel protein linked to the fragile X syndromeThe NIH Toolbox Cognitive Battery for intellectual disabilities: three preliminary studies and future directionsBehavioural phenotyping assays for mouse models of autismGABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism.Influence of stimulant-induced hyperactivity on social approach in the BTBR mouse model of autismImpaired critical period plasticity in primary auditory cortex of fragile X model miceMetabotropic glutamate receptors: from the workbench to the bedside.mGluR5 ablation in cortical glutamatergic neurons increases novelty-induced locomotionMouse models of autism: testing hypotheses about molecular mechanisms.The role of fragile X mental retardation protein in major mental disorders.Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO miceN-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia?Fragile X: a family of disorders.Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment.Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile X syndromeHyperactivity, perseveration and increased responding during attentional rule acquisition in the Fragile X mouse modelPharmacological rescue of cortical synaptic and network potentiation in a mouse model for fragile X syndromeAutism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathwayEpilepsy and Autism.Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome.Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc.Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismGroup I metabotropic glutamate receptor mediated dynamic immune dysfunction in children with fragile X syndrome.NIMH initiatives to facilitate collaborations among industry, academia, and government for the discovery and clinical testing of novel models and drugs for psychiatric disordersSuccessful cognitive aging in rats: a role for mGluR5 glutamate receptors, homer 1 proteins and downstream signaling pathways.
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Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 17 January 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Role for metabotropic glutamat ...... genesis of fragile X syndrome.
@en
Role for metabotropic glutamate receptor 5
@nl
type
label
Role for metabotropic glutamat ...... genesis of fragile X syndrome.
@en
Role for metabotropic glutamate receptor 5
@nl
prefLabel
Role for metabotropic glutamat ...... genesis of fragile X syndrome.
@en
Role for metabotropic glutamate receptor 5
@nl
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P1476
Role for metabotropic glutamat ...... genesis of fragile X syndrome.
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P2093
Mark F Bear
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P304
P356
10.1113/JPHYSIOL.2008.150722
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P577
2008-01-17T00:00:00Z