SIRT2 directs the replication stress response through CDK9 deacetylation. - Test2 - elhamkhani - TriplyDB

SIRT2 directs the replication stress response through CDK9 deacetylation.

SIRT2 directs the replication stress response through CDK9 deacetylation.

http://www.wikidata.org/entity/Q37103812

about

Sirtuins, metabolism, and DNA repair Sirtuins in epigenetic regulation Sirtuins in metabolism, DNA repair and cancer Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction.A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response Sirtuins and DNA damage repair: SIRT7 comes to play.ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA.Sirtuin regulation in aging and injury SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth Sirtuin 2 mutations in human cancers impair its function in genome maintenance.SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription Histone Modifications and Cancer.BRCA1 recruitment to damaged DNA sites is dependent on CDK9.Changes in microtubule-related proteins and autophagy in long-term vitamin E-deficient mice.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Sirtuins Expression and Their Role in Retinal Diseases.Nicotinamide Suppresses the DNA Damage Sensitivity of Saccharomyces cerevisiae Independently of Sirtuin Deacetylases.SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation.SIRT2 orchestrates the DNA damage response.Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1.Systematic Kinase Inhibitor Profiling Identifies CDK9 as a Synthetic Lethal Target in NUT Midline Carcinoma.Hexim1, an RNA-controlled protein hub.A stitch in time and CDK9.Protocols for Cloning, Expression, and Functional Analysis of Sirtuin2 (SIRT2).Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates.CDK9 Expression Shows Role as a Potential Prognostic Biomarker in Breast Cancer Patients Who Fail to Achieve Pathologic Complete Response after Neoadjuvant Chemotherapy The acetylation of cyclin-dependent kinase 5 at lysine 33 regulates kinase activity and neurite length in hippocampal neurons

P2860

Q27015759-476E7D4A-293E-4D94-8CE5-21E186989598 Q27026861-9EEAF628-BD9C-462A-976B-5BF0B9751C3C Q28070892-09F1B60C-B474-4E5B-9C90-660BBA9F9C73 Q33605950-0A53C294-6D30-4559-9681-3ADF6238C616 Q34313054-D462A394-B3A0-4F28-B437-EE7202020757 Q34555201-5F49C87B-B14E-4E6C-B018-4C7050131272 Q35917073-AD423ABE-2629-47B5-845E-5D4BBAEC916F Q36379286-301B87DA-8EB8-44FB-919C-98A4AE0B27BB Q37059824-5F8E9E59-B6E6-45F9-B399-A3DCFDF967A7 Q38705277-FFBE554C-45A0-4DCA-B4ED-E9382C88D391 Q38706788-A5EAEB29-4FEB-4876-9FD8-8162D5C464B6 Q38796064-BC08C5F7-2329-422C-A030-343D419B5B53 Q38917645-0EA9EBB2-1467-46EC-B3CD-2F0815BAED8E Q39020992-7A9FEC33-FF3F-4277-9A9B-00736828B541 Q39091771-16127639-2085-4D2C-A5E2-02B7A2AD7F26 Q39135669-509E75E8-8E42-48F9-A6CD-EF0E93450CB3 Q39488135-398DC000-9E49-42B3-9E1E-0BF60F34F9E8 Q40082412-AAE2BF9C-969D-48FD-BA2A-6929BD3748B3 Q40349749-0B4955A4-DBDE-4693-A10A-B54181BC15FD Q41449242-03C7256E-E5F7-4523-B5DC-152C9D7C4F97 Q41885791-43808351-C44A-44D1-ABFA-A293AC6F529C Q42367759-5512FF77-310D-4EA6-B1CD-D783CB1D36AF Q48219788-46AD768D-AA65-4637-BAC9-CCACB950432C Q50795257-582D9BFD-E56B-4ADB-95EE-198792CA3EEB Q51727680-A4AC0919-1A40-41DE-A9AD-31B68177FC77 Q55092857-18600895-B09C-4110-9276-DA45D14CA415 Q58567485-7C60297A-1BDA-4251-8511-63CAAFFEF361 Q58747585-2C18BA5D-0380-42A1-872D-8F54B9A57896

P2860

SIRT2 directs the replication stress response through CDK9 deacetylation.

http://www.wikidata.org/entity/Q37103812

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 29 July 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

SIRT2 directs the replication stress response through CDK9 deacetylation.

@en

SIRT2 directs the replication stress response through CDK9 deacetylation.

@nl

type

label

SIRT2 directs the replication stress response through CDK9 deacetylation.

@en

SIRT2 directs the replication stress response through CDK9 deacetylation.

@nl

prefLabel

SIRT2 directs the replication stress response through CDK9 deacetylation.

@en

SIRT2 directs the replication stress response through CDK9 deacetylation.

@nl

P1433

Q37103812-2890688E-9EE9-4A32-9333-79EC3513ADC6

P1476

Q37103812-FA966767-F11D-409A-8E78-DE35F16BE05F

P2093

Q37103812-3229FB7B-8F6B-4656-AFC3-85ADAAFBAE1A

Q37103812-37442D98-7041-4640-8C14-4018C6C8E507

Q37103812-38D128E6-9DB1-4FA3-B6F6-39D8D0D68E9C

Q37103812-3C3303EF-7CE3-4B78-8B3E-84608D4AE2BD

Q37103812-4FEBF1FB-AC20-40CA-B089-996EA832D7E8

Q37103812-AE9205FF-236B-48D2-A753-B23C24DAF010

Q37103812-C2A73B6E-44F7-4FBB-8B52-D8DB35689F7E

Q37103812-C8E2B5C9-2CA6-4855-A447-94764565BB58

Q37103812-D70AFDF9-18B8-4F68-B382-CB7A072408B7

Q37103812-EE66CB5B-FA83-4A1E-904E-38536584D8E5

P2860

Q37103812-217B1833-E932-47B0-8503-5DCD42B1A753

Q37103812-29A6D130-654C-4A81-A2DC-5D3B6A6CF31E

Q37103812-2E44DEC5-EA6D-4436-B011-25D92C36E9E4

Q37103812-340E057F-0E07-4E0D-9FDF-6FE03739143C

Q37103812-35599EAE-739A-4CA7-995B-034FFEC9BF80

Q37103812-359E6352-DDDC-4905-B6A0-7A352CD3773A

Q37103812-4A8CF74B-74E7-4768-9289-8C0D324EB5A9

Q37103812-56265784-82FE-491D-AC06-B0E317DCA9DE

Q37103812-5BCA28AE-1C3F-4F86-A059-F06F5C0FFD8C

Q37103812-5C9F9C6F-0C8C-4862-A282-2E02EEAF82CD

P304

Q37103812-505EF8C7-9F43-4219-A6D4-839E05D9B305

P31

Q37103812-394721B8-7423-4830-BFDD-9E68495A7B55

P356

Q37103812-A8B81434-2BFD-468C-B0DF-D79FE3CC338B

P407

Q37103812-B2AD927B-E31E-43E2-A4FC-D9F4926BA0A4

P433

Q37103812-285561CA-37CA-4A97-91E9-82F347BCAF83

P478

Q37103812-79E15D9E-E195-42FB-AF08-1D7F4DA04E42

P50

Q37103812-601E0063-1CB0-4717-AC5E-4AE1B41C3F90

P577

Q37103812-79C4759D-9BFA-4362-B9A6-733E34054672

P5875

Q37103812-D7C93566-3E0D-4253-B11C-E868CE1B05BB

P698

Q37103812-33F07585-E6C2-469C-9B06-E93C00AED1E0

P932

Q37103812-2309002A-7513-4C22-95A8-7F554FCCFC9C

P356

PNAS.1301463110

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

SIRT2 directs the replication stress response through CDK9 deacetylation

@en

P2093

Athanassios Vassilopoulos

http://www.w3.org/2001/XMLSchema#string

Brooke G Pantazides

http://www.w3.org/2001/XMLSchema#string

Claire W Hardy

http://www.w3.org/2001/XMLSchema#string

David Gius

http://www.w3.org/2001/XMLSchema#string

David S Yu

http://www.w3.org/2001/XMLSchema#string

Duc M Duong

http://www.w3.org/2001/XMLSchema#string

Hui Zhang

http://www.w3.org/2001/XMLSchema#string

Hyun-Seok Kim

http://www.w3.org/2001/XMLSchema#string

Matthew D Warren

http://www.w3.org/2001/XMLSchema#string

Nicholas T Seyfried

http://www.w3.org/2001/XMLSchema#string

P2860

SIRT1 regulates UV-induced DNA repair through deacetylating XPA

The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60

SIRT1 promotes DNA repair activity and deacetylation of Ku70

Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II

Human SIRT6 promotes DNA end resection through CtIP deacetylation

Cyclin-dependent kinase 9-cyclin K functions in the replication stress response

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

P304

13546-13551

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.1301463110

http://www.w3.org/2001/XMLSchema#string

P407

P433

33

http://www.w3.org/2001/XMLSchema#string

P478

110

http://www.w3.org/2001/XMLSchema#string

P50

Steven A Johnsen

P577

2013-07-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

253340234

http://www.w3.org/2001/XMLSchema#string

P698

23898190

http://www.w3.org/2001/XMLSchema#string

P932

3746840

http://www.w3.org/2001/XMLSchema#string