Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease.
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Loss of Sleep Affects the Ultrastructure of Pyramidal Neurons in the Adolescent Mouse Frontal CortexPolyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related DiseasesA deficiency of ceramide biosynthesis causes cerebellar purkinje cell neurodegeneration and lipofuscin accumulationTen years of Nature Reviews Neuroscience: insights from the highly citedInteractions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's diseaseReduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1Norepinephrine and its metabolites are involved in the synthesis of neuromelanin derived from the locus coeruleusPrincipal Component Analysis of Multimodal Neuromelanin MRI and Dopamine Transporter PET Data Provides a Specific Metric for the Nigral Dopaminergic Neuronal DensityNeuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's diseaseSynthesis and structural characterization of soluble neuromelanin analogs provides important clues to its biosynthesis.Loss of spatacsin function alters lysosomal lipid clearance leading to upper and lower motor neuron degenerationExpression of varicella-zoster virus immediate-early regulatory protein IE63 in neurons of latently infected human sensory ganglia.Trace metal imaging with high spatial resolution: applications in biomedicine.Deficiency of prion protein induces impaired autophagic flux in neurons.Distinct pathogenic processes between Fig4-deficient motor and sensory neurons.Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits.Lipofuscin in human glaucomatous optic nerves.Aging and its modulation in a long-lived worker caste of the honey beeSIRT1 regulation of wakefulness and senescence-like phenotype in wake neuronsHIV-1 Tat activates a RhoA signaling pathway to reduce NMDA-evoked calcium responses in hippocampal neurons via an actin-dependent mechanismDistinct types of lipofuscin pigment in the hippocampus and cerebellum of aged cheirogaleid primates.Evidence for aberrant astrocyte hemichannel activity in Juvenile Neuronal Ceroid Lipofuscinosis (JNCL).PGC-1α activity in nigral dopamine neurons determines vulnerability to α-synucleinLipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration.Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease.Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2.Neuromelanin in parkinsonian disorders: an update.Bent out of shape: α-Synuclein misfolding and the convergence of pathogenic pathways in Parkinson's disease.Somatic RET mutation in a patient with pigmented adrenal pheochromocytoma.Fig4 deficiency: a newly emerged lysosomal storage disorder?Intermittent Short Sleep Results in Lasting Sleep Wake Disturbances and Degeneration of Locus Coeruleus and Orexinergic NeuronsDetoxification reactions: relevance to aging.Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neuronsOxidative damage and cellular defense mechanisms in sea urchin models of agingMobilization of stored iron in mammals: a review.Whole-genome sequencing of eight goat populations for the detection of selection signatures underlying production and adaptive traits.Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype.Longevity of human islet α- and β-cells.Lewy pathology and neurodegeneration in premotor Parkinson's disease.
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P2860
Neuronal pigmented autophagic vacuoles: lipofuscin, neuromelanin, and ceroid as macroautophagic responses during aging and disease.
description
article científic
@ca
article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on April 2008
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Neuronal pigmented autophagic ...... nses during aging and disease.
@en
Neuronal pigmented autophagic ...... nses during aging and disease.
@nl
type
label
Neuronal pigmented autophagic ...... nses during aging and disease.
@en
Neuronal pigmented autophagic ...... nses during aging and disease.
@nl
prefLabel
Neuronal pigmented autophagic ...... nses during aging and disease.
@en
Neuronal pigmented autophagic ...... nses during aging and disease.
@nl
P2093
P2860
P1476
Neuronal pigmented autophagic ...... nses during aging and disease.
@en
P2093
David Sulzer
Eugene Mosharov
John D Simon
Luigi Zecca
Zsolt Talloczy
P2860
P356
10.1111/J.1471-4159.2008.05385.X
P407
P577
2008-04-01T00:00:00Z