Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
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Bacterial artificial chromosome mutagenesis using recombineeringIdentification of the mammalian homologues of the Drosophila timeless gene, Timeless1A bacterial artificial chromosome library for sequencing the complete human genomeDisruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in miceMutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden miceA noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivoBiography of Joseph S. TakahashiPERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues.The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic developmentThe NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian controlObesity and metabolic syndrome in circadian Clock mutant miceOscillating perceptions: the ups and downs of the CLOCK protein in the mouse circadian systemA phenotype-based screen for embryonic lethal mutations in the mouse.Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2Simple and highly efficient BAC recombineering using galK selectionRapid and quantitative detection of homologous and non-homologous recombination events using three oligonucleotide MLPA.Construction and characterization of a genomic BAC library for the Mus m. musculus mouse subspecies (PWD/Ph inbred strain).Pharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapyUsing mouse models to study function of transcriptional factors in T cell developmentControlling complexity: the clinical relevance of mouse complex geneticsBrain-specific rescue of Clock reveals system-driven transcriptional rhythms in peripheral tissueCrystal Structure of the Heterodimeric CLOCK:BMAL1 Transcriptional Activator ComplexControl of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells.Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome.Cryptochrome and Period Proteins Are Regulated by the CLOCK/BMAL1 Gene: Crosstalk between the PPARs/RXRalpha-Regulated and CLOCK/BMAL1-Regulated Systems.The Implications of Multiple Circadian Clock OriginsManipulating the circadian and sleep cycles to protect against metabolic diseaseMolecular components of the circadian clock in mammalsCloning and characterization of rat casein kinase 1epsilonPositional syntenic cloning and functional characterization of the mammalian circadian mutation tau.Positional cloning of the mouse circadian clock geneA non-canonical E-box within the MyoD core enhancer is necessary for circadian expression in skeletal muscleConserved regions of the timeless (tim) clock gene in Drosophila analyzed through phylogenetic and functional studiesChromosome 21 and down syndrome: from genomics to pathophysiologyPositional cloning of the mouse saccharin preference (Sac) locusAn Oak Ridge legacy: the specific locus test and its role in mouse mutagenesisThe circadian clock in cancer development and therapyRescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital developmentProtein phosphatase PHLPP1 controls the light-induced resetting of the circadian clockdsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice
P2860
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P2860
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1997
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
@en
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
@nl
type
label
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
@en
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
@nl
prefLabel
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
@en
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
@nl
P2093
P2860
P1433
P1476
Functional identification of the mouse circadian Clock gene by transgenic BAC rescue.
@en
P2093
A M Sangoram
J S Takahashi
L D Wilsbacher
M H Vitaterna
M P Antoch
P2860
P304
P356
10.1016/S0092-8674(00)80246-9
P407
P577
1997-05-01T00:00:00Z