Cloning and characterization of the biosynthetic gene cluster for tomaymycin, an SJG-136 monomeric analog.
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Kinetic, Crystallographic, and Mechanistic Characterization of TomN: Elucidation of a Function for a 4-Oxalocrotonate Tautomerase Homologue in the Tomaymycin Biosynthetic PathwayStructure and activity of NADPH-dependent reductase Q1EQE0 from Streptomyces kanamyceticus, which catalyses the R-selective reduction of an imine substrateAdaptation of an L-proline adenylation domain to use 4-propyl-L-proline in the evolution of lincosamide biosynthesisIdentification and characterization of new family members in the tautomerase superfamily: analysis and implicationsAnthranilate-activating modules from fungal nonribosomal peptide assembly linesAminobenzoates as building blocks for natural product assembly lines.Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis.Identification of the dioxygenase-generated intermediate formed during biosynthesis of the dihydropyrrole moiety common to anthramycin and sibiromycinLincomycin biosynthesis involves a tyrosine hydroxylating heme protein of an unusual enzyme family.Lincosamide synthetase--a unique condensation system combining elements of nonribosomal peptide synthetase and mycothiol metabolism.Mutasynthesis of a potent anticancer sibiromycin analoguePhysiology, Biochemistry, and Applications of F420- and Fo-Dependent Redox Reactions.Biosynthesis of sibiromycin, a potent antitumor antibiotic.Short pathways to complexity generation: fungal peptidyl alkaloid multicyclic scaffolds from anthranilate building blocks.Biosynthesis, synthesis, and biological activities of pyrrolobenzodiazepinesA heme peroxidase with a functional role as an L-tyrosine hydroxylase in the biosynthesis of anthramycin.New Concept of the Biosynthesis of 4-Alkyl-L-Proline Precursors of Lincomycin, Hormaomycin, and Pyrrolobenzodiazepines: Could a γ-Glutamyltransferase Cleave the C-C Bond?Genome Mining of Streptomyces sp. Tü 6176: Characterization of the Nataxazole Biosynthesis Pathway.Discovery and characterization of an F420-dependent glucose-6-phosphate dehydrogenase (Rh-FGD1) from Rhodococcus jostii RHA1.The methanogenic redox cofactor F420 is widely synthesized by aerobic soil bacteria.Co-overexpression of lmbW and metK led to increased lincomycin A production and decreased byproduct lincomycin B content in an industrial strain of Streptomyces lincolnensis.4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavageSequence analysis of porothramycin biosynthetic gene cluster.Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci.Discovery of 3-formyl-tyrosine metabolites from Pseudoalteromonas tunicata through heterologous expression.The novel transcriptional regulator LmbU promotes lincomycin biosynthesis through regulating expression of its target genes in Streptomyces lincolnensis.Evolution-guided adaptation of an adenylation domain substrate specificity to an unusual amino acid.Biosynthesis of the Enterotoxic Pyrrolobenzodiazepine Natural Product Tilivalline.Isolation and characterization of indigenous Streptomyces and Lentzea strains from soils containing boron compounds in Argentina.Synthesis of novel ligands targeting phenazine biosynthesis proteins as a strategy for antibiotic intervention.InspIRED by Nature: NADPH-Dependent Imine Reductases (IREDs) as Catalysts for the Preparation of Chiral Amines.The benzodiazepine-like natural product tilivalline is produced by the entomopathogenic bacterium Xenorhabdus eapokensis.Comparative Genomics and Biosynthetic Potential Analysis of Two Lichen-Isolated Amycolatopsis Strains.Novel pathway of 3-hydroxyanthranilic acid formation in limazepine biosynthesis reveals evolutionary relation between phenazines and pyrrolobenzodiazepines.C-C bond cleavage in biosynthesis of 4-alkyl-L-proline precursors of lincomycin and anthramycin cannot precede C-methylation
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Cloning and characterization of the biosynthetic gene cluster for tomaymycin, an SJG-136 monomeric analog.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cloning and characterization o ...... , an SJG-136 monomeric analog.
@en
Cloning and characterization o ...... , an SJG-136 monomeric analog.
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type
label
Cloning and characterization o ...... , an SJG-136 monomeric analog.
@en
Cloning and characterization o ...... , an SJG-136 monomeric analog.
@nl
prefLabel
Cloning and characterization o ...... , an SJG-136 monomeric analog.
@en
Cloning and characterization o ...... , an SJG-136 monomeric analog.
@nl
P2093
P2860
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P1476
Cloning and characterization o ...... , an SJG-136 monomeric analog.
@en
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Ankush Khullar
Barbara Gerratana
ShenChieh Chou
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P304
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10.1128/AEM.02325-08
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P577
2009-03-06T00:00:00Z