"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
about
Cwc24p is a general Saccharomyces cerevisiae splicing factor required for the stable U2 snRNP binding to primary transcriptsThe RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complexRNA helicases at work: binding and rearrangingSplicing fidelity: DEAD/H-box ATPases as molecular clocksNew insights into the spliceosome by single molecule fluorescence microscopyVisualizing Group II Intron Catalysis through the Stages of SplicingU2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.Structure of the yeast U2/U6 snRNA complexCancer-relevant Splicing Factor CAPERĪ± Engages the Essential Splicing Factor SF3b155 in a Specific Ternary ComplexCryo-EM structure of the spliceosome immediately after branchingConformational dynamics of stem II of the U2 snRNA.Splicing proofreading at 5' splice sites by ATPase Prp28p.CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome.Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factorsSpliceosome Structure and FunctionExpansion of the eukaryotic proteome by alternative splicingParticular significance of SRD2-dependent snRNA accumulation in polarized pattern generation during lateral root development of Arabidopsis.Rapid cross-linking of an RNA internal loop by the anticancer drug cisplatinmRNA secondary structures fold sequentially but exchange rapidly in vivo.Variable phenotypic expressivity in a Swiss family with autosomal dominant retinitis pigmentosa due to a T494M mutation in the PRPF3 geneA bird's-eye view of post-translational modifications in the spliceosome and their roles in spliceosome dynamicsAn antisense microwalk reveals critical role of an intronic position linked to a unique long-distance interaction in pre-mRNA splicingGenomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance.Modelling reveals kinetic advantages of co-transcriptional splicingThe RNA backbone plays a crucial role in mediating the intrinsic stability of the GpU dinucleotide platform and the GpUpA/GpA miniduplex.Ribonucleoprotein multimers and their functions.Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis.Predicting folding pathways between RNA conformational structures guided by RNA stacks.DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps.Mechanisms and Regulation of Alternative Pre-mRNA SplicingProofreading and spellchecking: a two-tier strategy for pre-mRNA splicing quality control.Regulation of alternative splicing by the core spliceosomal machinery.The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region.Constant splice-isoform ratios in human lymphoblastoid cells support the concept of a splico-statAlternative splicing in multiple sclerosis and other autoimmune diseases.Diverse mechanisms for spliceosome-mediated 3' end processing of telomerase RNA.The spliceosomal PRP19 complex of trypanosomesReflections on the theory of "silver bullet" octreotide tracers: implications for ligand-receptor interactions in the age of peptides, heterodimers, receptor mosaics, truncated receptors, and multifractal analysis.A U1-U2 snRNP interaction network during intron definitionRegulatory Divergence of Transcript Isoforms in a Mammalian Model System.
P2860
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P2860
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
description
article cientĆfic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo cientĆfico
@pt
bilimsel makale
@tr
scientific article published on June 2008
@en
vedeckĆ½ ÄlĆ”nok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vÄdeckĆ½ ÄlĆ”nek
@cs
name
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
@en
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
@nl
type
label
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
@en
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
@nl
prefLabel
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
@en
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
@nl
P2860
P1433
P1476
"Nought may endure but mutability": spliceosome dynamics and the regulation of splicing.
@en
P2093
Charles C Query
Maria M Konarska
P2860
P304
P356
10.1016/J.MOLCEL.2008.04.013
P577
2008-06-01T00:00:00Z