Targeting hedgehog signaling in cancer: research and clinical developments.
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Multiple myeloma cancer stem cellsThe Role of miRNAs in the Regulation of Pancreatic Cancer Stem CellsCancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?NANOMEDICINE: will it offer possibilities to overcome multiple drug resistance in cancer?Seeking genetic signature of radiosensitivity--a novel method for data analysis in case of small sample sizes.Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathwaysCombined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia.CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide.Treatment response in the PIVENS trial is associated with decreased Hedgehog pathway activity.Intervention in the context of development: pathways toward new treatments.Genome-wide microarray expression and genomic alterations by array-CGH analysis in neuroblastoma stem-like cells.Synergistic inhibition of colon carcinoma cell growth by Hedgehog-Gli1 inhibitor arsenic trioxide and phosphoinositide 3-kinase inhibitor LY294002.FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling.Histone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma.Nanoquinacrine induced apoptosis in cervical cancer stem cells through the inhibition of hedgehog-GLI1 cascade: Role of GLI-1Contextualizing the Genes Altered in Bladder Neoplasms in Pediatric andTeen Patients Allows Identifying Two Main Classes of Biological ProcessesInvolved and New Potential Therapeutic TargetsPharmacological evaluation of a series of smoothened antagonists in signaling pathways and after topical application in a depilated mouse modelSonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.A sesquiterpene lactone from Siegesbeckia glabrescens suppresses Hedgehog/Gli-mediated transcription in pancreatic cancer cells.New insight into hedgehog signaling in hematological malignancies.SHH inhibitors for the treatment of medulloblastoma.Effect of Hedgehog Signaling Pathway Activation on Proliferation of High-Grade Gliomas.The hedgehog/Gli-1 signaling pathways is involved in the inhibitory effect of resveratrol on human colorectal cancer HCT116 cells.Gorlin syndrome-derived induced pluripotent stem cells are hypersensitive to hedgehog-mediated osteogenic induction.Zhi Zhen Fang formula reverses Hedgehog pathway mediated multidrug resistance in colorectal cancer.Relationship between Hedgehog Signaling Pathway and Drug Resistance of Poorly Differentiated Gliomas.Comparative genomic analysis of intracranial germ cell tumors - the preliminary study focused on Sonic Hedgehog signaling pathway.Activation of hedgehog signaling and its association with cisplatin resistance in ovarian epithelial tumors.
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P2860
Targeting hedgehog signaling in cancer: research and clinical developments.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 October 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Targeting hedgehog signaling in cancer: research and clinical developments.
@en
Targeting hedgehog signaling in cancer: research and clinical developments.
@nl
type
label
Targeting hedgehog signaling in cancer: research and clinical developments.
@en
Targeting hedgehog signaling in cancer: research and clinical developments.
@nl
prefLabel
Targeting hedgehog signaling in cancer: research and clinical developments.
@en
Targeting hedgehog signaling in cancer: research and clinical developments.
@nl
P2093
P2860
P356
P1476
Targeting hedgehog signaling in cancer: research and clinical developments.
@en
P2093
Christopher M Bartels
Dongsheng Gu
Jingwu Xie
Scott W Barton
P2860
P304
P356
10.2147/OTT.S34678
P407
P577
2013-10-10T00:00:00Z