Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome. - Test2 - elhamkhani - TriplyDB

Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.

Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.

http://www.wikidata.org/entity/Q37262646

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Genes that regulate morphogenesis and growth of the temporomandibular joint: a review Interaction of TGFβ and BMP signaling pathways during chondrogenesis Identification of the GATA factor TRPS1 as a repressor of the osteocalcin promoter.Characterization of the chromosomal inversion associated with the Koa mutation in the mouse revealed the cause of skeletal abnormalities Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.A novel TRPS1 mutation in a Moroccan family with Tricho-rhino-phalangeal syndrome type III: case report Association of TRPS1 gene with different EMT markers in ERα-positive and ERα-negative breast cancer.Dentin sialophosphoprotein in biomineralization A novel TRPS1 gene mutation causing trichorhinophalangeal syndrome with growth hormone responsive short stature: a case report and review of the literature.Dual role of the Trps1 transcription factor in dentin mineralization.The histone methyltransferase inhibitor BIX01294 enhances the cardiac potential of bone marrow cells.A central role for TRPS1 in the control of cell cycle and cancer development.Losartan increases bone mass and accelerates chondrocyte hypertrophy in developing skeleton.Transforming growth factor beta signaling in adult cardiovascular diseases and repair.Control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2.Transcriptional repression of the Dspp gene leads to dentinogenesis imperfecta phenotype in Col1a1-Trps1 transgenic mice.Exome sequencing identifies de novo pathogenic variants in FBN1 and TRPS1 in a patient with a complex connective tissue phenotype.The Role of Tricho-Rhino-Phalangeal Syndrome (TRPS) 1 in Apoptosis during Embryonic Development and Tumor Progression.Down-regulation of TRPS1 stimulates epithelial-mesenchymal transition and metastasis through repression of FOXA1.Transcriptional control of chondrocyte specification and differentiation.Silencing of anti-chondrogenic microRNA-221 in human mesenchymal stem cells promotes cartilage repair in vivo.Trichorhinophalangeal Syndrome Type I: A Patient with Two Novel and Different Mutations in the TRPS1 Gene.The multi zinc-finger protein Trps1 acts as a regulator of histone deacetylation during mitosis.Somatic mosaicism in trichorhinophalangeal syndrome: a lesson for genetic counseling.Identification of a new mutation in TRPS1 gene leading to tricho-rhino-phalangeal syndrome I in a Chinese patient.Expression and relevance of TRPS-1: a new GATA transcription factor in breast cancer.Human stanniocalcin-1 or -2 expressed in mice reduces bone size and severely inhibits cranial intramembranous bone growth.Fate mapping of Trps1 daughter cells during cardiac development using novel Trps1-Cre mice.A novel de novo nonsense mutation in the TRPS1 gene in a Japanese patient with tricho-rhino-phalangeal syndrome type I.Trps1 is associated with the multidrug resistance of lung cancer cell by regulating MGMT gene expression.Trps1 is necessary for normal temporomandibular joint development.Third case of 8q23.3-q24.13 deletion in a patient with Langer-Giedion syndrome phenotype without TRPS1 gene deletion.Unexpected exome sequencing result: de novo TRPS1 mutation in an infant with infantile scoliosis, mild developmental delay, and history of consanguinity MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells

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Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.

http://www.wikidata.org/entity/Q37262646

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 17 April 2008

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Uncoupling of chondrocyte diff ...... cho-rhino-phalangeal syndrome.

@en

Uncoupling of chondrocyte diff ...... cho-rhino-phalangeal syndrome.

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type

label

Uncoupling of chondrocyte diff ...... cho-rhino-phalangeal syndrome.

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Uncoupling of chondrocyte diff ...... cho-rhino-phalangeal syndrome.

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prefLabel

Uncoupling of chondrocyte diff ...... cho-rhino-phalangeal syndrome.

@en

Uncoupling of chondrocyte diff ...... cho-rhino-phalangeal syndrome.

@nl

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Human Molecular Genetics

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Uncoupling of chondrocyte diff ...... icho-rhino-phalangeal syndrome

@en

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Brendan Lee

http://www.w3.org/2001/XMLSchema#string

Elda Munivez

http://www.w3.org/2001/XMLSchema#string

Kathy Sam

http://www.w3.org/2001/XMLSchema#string

Qiping Zheng

http://www.w3.org/2001/XMLSchema#string

Ramesh A Shivdasani

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Roy Morello

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P2860

Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

Developmental regulation of the growth plate

Dysregulation of chondrogenesis in human cleidocranial dysplasia

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2244-2254

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scholarly article

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10.1093/HMG/DDN125

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14

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17

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Dobrawa Napierala

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2008-04-17T00:00:00Z

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18424451

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2710999

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