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Highly efficient targeted mutagenesis in mice using TALENs

Highly efficient targeted mutagenesis in mice using TALENs

http://www.wikidata.org/entity/Q37269781

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Genome Engineering with TALE and CRISPR Systems in Neuroscience Revisiting the TALE repeat TALEN-mediated gene mutagenesis in rhesus and cynomolgus monkeys.Production of CMAH Knockout Preimplantation Embryos Derived From Immortalized Porcine Cells Via TALE Nucleases.TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity Next-generation mammalian genetics toward organism-level systems biology Highly efficient targeted mutagenesis in one-cell mouse embryos mediated by the TALEN and CRISPR/Cas systems.Efficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases.Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing TALEN and CRISPR/Cas Genome Editing Systems: Tools of Discovery.Development of an intein-mediated split-Cas9 system for gene therapy Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.Mouse Genome Editing Using the CRISPR/Cas System.RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency C9orf72 ablation in mice does not cause motor neuron degeneration or motor deficits.Translating human genetics into mouse: the impact of ultra-rapid in vivo genome editing.TALEN-mediated genome engineering to generate targeted mice.Mouse Genome Informatics (MGI) Resource: Genetic, Genomic, and Biological Knowledgebase for the Laboratory Mouse.FTD and ALS--translating mouse studies into clinical trials.Modeling human epilepsy by TALEN targeting of mouse sodium channel Scn8a.Molecular basis of ALS and FTD: implications for translational studies.A history of genome editing in mammals.TALE of an SCN8A-Associated Epileptic Encephalopathy Mouse Model.Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases.Biological Spectrum of Amyotrophic Lateral Sclerosis Prions.Generation of Foxo3-targeted Mice by Injection of mRNAs Encoding Transcription Activator-like Effector Nucleases (TALENs) into Zygotes.Generation of knockout mice by Cpf1-mediated gene targeting.

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Highly efficient targeted mutagenesis in mice using TALENs

http://www.wikidata.org/entity/Q37269781

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 26 August 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Highly efficient targeted mutagenesis in mice using TALENs

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Highly efficient targeted mutagenesis in mice using TALENs.

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type

label

Highly efficient targeted mutagenesis in mice using TALENs

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Highly efficient targeted mutagenesis in mice using TALENs.

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prefLabel

Highly efficient targeted mutagenesis in mice using TALENs

@en

Highly efficient targeted mutagenesis in mice using TALENs.

@nl

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GENETICS.113.156570

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Highly efficient targeted mutagenesis in mice using TALENs

@en

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Benedikt Wefers

http://www.w3.org/2001/XMLSchema#string

Bettina Schmid

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Oskar Ortiz

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Sudeepta Kumar Panda

http://www.w3.org/2001/XMLSchema#string

Thomas Floss

http://www.w3.org/2001/XMLSchema#string

Wolfgang Wurst

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P2860

Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases

Site specific mutation of the Zic2 locus by microinjection of TALEN mRNA in mouse CD1, C3H and C57BL/6J oocytes

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

Knockout rats via embryo microinjection of zinc-finger nucleases

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

A simple cipher governs DNA recognition by TAL effectors

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703-713

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scholarly article

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10.1534/GENETICS.113.156570

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3

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195

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Christian Haass

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2013-08-26T00:00:00Z

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256119580

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23979585

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3813858

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