Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.
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A novel multiplexed, image-based approach to detect phenotypes that underlie chromosome instability in human cellsMechanisms of a novel anticancer therapeutic strategy involving atmospheric pressure plasma-mediated apoptosis and DNA strand break formation.Characterizing the prevalence of chromosome instability in interval colorectal cancerThe Overexpression of FEN1 and RAD54B May Act as Independent Prognostic Factors of Lung Adenocarcinoma.Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells.The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition.Unraveling new functions of superoxide dismutase using yeast model system: Beyond its conventional role in superoxide radical scavenging.Mitotic accumulation of dimethylated lysine 79 of histone H3 is important for maintaining genome integrity during mitosis in human cells.The enigmatic oncogene and tumor suppressor-like properties of RAD54B: Insights into genome instability and cancer.Chromosomal instability causes sensitivity to metabolic stress.Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer.KIF11 silencing and inhibition induces chromosome instability that may contribute to cancer.Convergence of miR-143 overexpression, oxidative stress and cell death in HCT116 human colon cancer cells.Synthetic lethal targeting of RNF20 through PARP1 silencing and inhibition.
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Synthetic lethal targeting of superoxide dismutase 1 selectively kills RAD54B-deficient colorectal cancer cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Synthetic lethal targeting of ...... cient colorectal cancer cells.
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Synthetic lethal targeting of ...... cient colorectal cancer cells.
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type
label
Synthetic lethal targeting of ...... cient colorectal cancer cells.
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Synthetic lethal targeting of ...... cient colorectal cancer cells.
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prefLabel
Synthetic lethal targeting of ...... cient colorectal cancer cells.
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Synthetic lethal targeting of ...... cient colorectal cancer cells.
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Synthetic lethal targeting of ...... cient colorectal cancer cells.
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Babu V Sajesh
Melanie Bailey
Philip Hieter
Zelda Lichtensztejn
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P356
10.1534/GENETICS.113.156836
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P577
2013-09-03T00:00:00Z