Neutrophils mediate antibody-induced antitumor effects in mice. - Test2 - elhamkhani - TriplyDB

Neutrophils mediate antibody-induced antitumor effects in mice.

Neutrophils mediate antibody-induced antitumor effects in mice.

http://www.wikidata.org/entity/Q37272029

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Influence of immunoglobulin isotype on therapeutic antibody function Neutrophils and Granulocytic MDSC: The Janus God of Cancer Immunotherapy Macrophages eliminate circulating tumor cells after monoclonal antibody therapy A FcγRIII-engaging bispecific antibody expands the range of HER2-expressing breast tumors eligible to antibody therapy.Fusion of CTLA-4 with HPV16 E7 and E6 enhanced the potency of therapeutic HPV DNA vaccine.IL-1 Contributes to the Anti-Cancer Efficacy of Ingenol Mebutate.MET is required for the recruitment of anti-tumoural neutrophils Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding Suppression of established hepatocarcinoma in adjuvant only immunotherapy: alum triggers anti-tumor CD8+ T cell response Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells.Durable antitumor responses to CD47 blockade require adaptive immune stimulation.Prognostic relevance of HER2/neu in acute lymphoblastic leukemia and induction of NK cell reactivity against primary ALL blasts by trastuzumab Long-term intravital imaging of the multicolor-coded tumor microenvironment during combination immunotherapy.Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses.Three major uncertainties in the antibody therapy of cancer.Regulation of neutrophil functions through inhibitory receptors: an emerging paradigm in health and disease.Mouse and human FcR effector functions.bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.FcγR requirements leading to successful immunotherapy.Increasing FcγRIIa affinity of an FcγRIII-optimized anti-EGFR antibody restores neutrophil-mediated cytotoxicity.Pro- and anti-tumour effects of B cells and antibodies in cancer: a comparison of clinical studies and preclinical models.Effect of trastuzumab interchain disulfide bond cleavage on Fcγ receptor binding and antibody-dependent tumour cell phagocytosis.The CD47-SIRPα signaling axis as an innate immune checkpoint in cancer.Neutrophils in cancer.Development of immunomonitoring of antibody‑dependent cellular cytotoxicity against neuroblastoma cells using whole blood.Tumor location determines tissue-specific recruitment of tumor-associated macrophages and antibody-dependent immunotherapy response.Nanoparticle Targeting of Neutrophils for Improved Cancer Immunotherapy.Roles for Innate Immunity in Combination Immunotherapies.Therapeutic Antibodies: What Have We Learnt from Targeting CD20 and Where Are We Going?Neutrophils in Gliomas.The humanized anti-human AMHRII mAb 3C23K exerts an anti-tumor activity against human ovarian cancer through tumor-associated macrophages.Advantages with prophylactic PEG-rhG-CSF versus rhG-CSF in breast cancer patients receiving multiple cycles of myelosuppressive chemotherapy: an open-label, randomized, multicenter phase III study.PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody.An Fc-optimized CD133 antibody for induction of NK cell reactivity against myeloid leukemia.Fc-Gamma receptor polymorphism and gene expression of peripheral blood mononuclear cells in patients with HER2-positive metastatic breast cancer receiving single-agent trastuzumab.Neutrophils are essential for induction of vaccine-like effects by antiviral monoclonal antibody immunotherapies.

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Neutrophils mediate antibody-induced antitumor effects in mice.

http://www.wikidata.org/entity/Q37272029

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 26 August 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Neutrophils mediate antibody-induced antitumor effects in mice.

@en

Neutrophils mediate antibody-induced antitumor effects in mice.

@nl

type

label

Neutrophils mediate antibody-induced antitumor effects in mice.

@en

Neutrophils mediate antibody-induced antitumor effects in mice.

@nl

prefLabel

Neutrophils mediate antibody-induced antitumor effects in mice.

@en

Neutrophils mediate antibody-induced antitumor effects in mice.

@nl

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BLOOD-2013-04-497446

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Neutrophils mediate antibody-induced antitumor effects in mice

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Bruno Iannascoli

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Clifford A Lowell

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David A Mancardi

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Friederike Jönsson

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Laurence Fiette

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P2860

In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days

Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection

Comparison of IgE and IgG antibody-dependent cytotoxicity in vitro and in a SCID mouse xenograft model of ovarian carcinoma.

The role of the human Fc receptor Fc gamma RIIA in the immune clearance of platelets: a transgenic mouse model.

Monoclonal antibodies: versatile platforms for cancer immunotherapy.

Neutrophils as effector cells for antibody-based immunotherapy of cancer.

Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo.

Phagocytosis and innate immunity.

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

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3160-3164

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10.1182/BLOOD-2013-04-497446

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James P Di Santo

Marcello Albanesi

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2013-08-26T00:00:00Z

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