The potential of histone deacetylase inhibitors in Niemann - Pick type C disease. - Test2 - elhamkhani - TriplyDB

The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

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Epigenetic regulation of cholesterol homeostasis.Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.Sphingolipids and mitochondrial function, lessons learned from yeast Modeling Niemann Pick type C1 using human embryonic and induced pluripotent stem cells.FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.Generation of patient specific human neural stem cells from Niemann-Pick disease type C patient-derived fibroblasts.

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The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

http://www.wikidata.org/entity/Q37380311

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 23 September 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

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The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

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type

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The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

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The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

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prefLabel

The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

@en

The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

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The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.

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Michael Maceyka

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Sheldon Milstien

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P2860

Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression

NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes

Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease

Structure of N-Terminal Domain of NPC1 Reveals Distinct Subdomains for Binding and Transfer of Cholesterol

Accumulation of glycosphingolipids in Niemann-Pick C disease disrupts endosomal transport

Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding

Sphingosine-1-phosphate: an enigmatic signalling lipid

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6367-6372

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scholarly article

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10.1111/FEBS.12505

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