The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
about
Epigenetic regulation of cholesterol homeostasis.Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.Sphingolipids and mitochondrial function, lessons learned from yeastModeling Niemann Pick type C1 using human embryonic and induced pluripotent stem cells.FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.Generation of patient specific human neural stem cells from Niemann-Pick disease type C patient-derived fibroblasts.
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The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 23 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
@en
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
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type
label
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
@en
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
@nl
prefLabel
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
@en
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
@nl
P2860
P356
P1433
P1476
The potential of histone deacetylase inhibitors in Niemann - Pick type C disease.
@en
P2093
Michael Maceyka
Sheldon Milstien
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P304
P356
10.1111/FEBS.12505
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P577
2013-09-23T00:00:00Z