Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. - Test2 - elhamkhani - TriplyDB

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

http://www.wikidata.org/entity/Q37391969

about

Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries S-nitrosylation in cardiovascular signaling Nitric oxide synthases in heart failure Arginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-Atherosclerosis Selective endothelial overexpression of arginase II induces endothelial dysfunction and hypertension and enhances atherosclerosis in mice Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice Chronic oral administration of the arginase inhibitor 2(S)-amino-6-boronohexanoic acid (ABH) improves erectile function in aged rats.European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).Effects of aging on angiogenesis.Bothrops jararaca peptide with anti-hypertensive action normalizes endothelium dysfunction involved in physiopathology of preeclampsia.Ascorbic acid or L-arginine improves cutaneous microvascular function in chronic kidney disease.Upregulation of inducible nitric oxide synthase contributes to attenuated cutaneous vasodilation in essential hypertensive humans.Functions of arginase isoforms in macrophage inflammatory responses: impact on cardiovascular diseases and metabolic disorders.Enteral arginase II provides ornithine for citrulline synthesis.In vivo assessment of arterial stiffness in the isoflurane anesthetized spontaneously hypertensive rat.Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans.New approaches to the design and discovery of therapies to prevent erectile dysfunction.Nox2-dependent glutathionylation of endothelial NOS leads to uncoupled superoxide production and endothelial barrier dysfunction in acute lung injury.Arginase in retinopathy.Efficacy of female rat models in translational cardiovascular aging research Akita spontaneously type 1 diabetic mice exhibit elevated vascular arginase and impaired vascular endothelial and nitrergic function.Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging.Arterial Stiffness Superoxide signaling in perivascular adipose tissue promotes age-related artery stiffness.Mechanisms of improved aortic stiffness by arotinolol in spontaneously hypertensive rats.Effect of arginase inhibition on pulmonary L-arginine metabolism in murine Pseudomonas pneumonia Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness.Arginase inhibition enhances angiogenesis in endothelial cells exposed to hypoxia.Effect of arginase inhibition on ischemia-reperfusion injury in patients with coronary artery disease with and without diabetes mellitus.Angiotensin II-induced arterial thickening, fibrosis and stiffening involves elevated arginase function Oral atorvastatin therapy increases nitric oxide-dependent cutaneous vasodilation in humans by decreasing ascorbate-sensitive oxidants Role of nitric oxide in placental vascular development and function.p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-uncoupling in obesity Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway.The effects of arginase inhibitor on lung oxidative stress and inflammation caused by pneumoperitoneum in rats.Role of interferon alpha in endothelial dysfunction: insights into endothelial nitric oxide synthase-related mechanisms Vascular Aging in Women: is Estrogen the Fountain of Youth?Differential modulation of nitric oxide synthases in aging: therapeutic opportunities.Arginase II inhibition prevents nitrate tolerance.Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice.

P2860

Q23909575-363577E5-9674-4596-959F-3A46813BD570 Q24630263-EAC34C51-D452-400B-B12D-632FBF2644C0 Q26830146-35946522-753C-4A95-88C6-35E5CA57663F Q26991946-71411C72-B601-416F-ACFD-A696E13F8B6A Q28386564-42BD17E5-4205-47BF-8A7E-60D2463249A0 Q28390561-EB5CD141-5B9C-4998-A2C6-4393953C2FB2 Q33642371-77453208-4E63-4C64-A42B-6DFEBBC0ED15 Q33761211-17A141D8-EA93-4D70-B9A9-21799F08E09F Q33914406-95B8B8F3-1674-45E0-A210-B97D6C5E69DB Q33999976-E8A9172B-7F61-4F6C-BC10-721D9472E20A Q34008329-36456C77-6396-43BD-90C8-55BCA96C00A1 Q34022778-EFC99672-9FC1-43A0-8F6E-CEE514B91CA5 Q34406933-E51F9D40-5B49-43EF-831A-B04D1F8F40CF Q34501755-8EEF0569-B350-44FC-B157-A240CFC6D9DF Q34576393-4F30E667-30D0-4C8B-B7FF-9155B5363A7D Q34617217-FE5F88C0-7796-4330-8F5B-03C73FBE6F6D Q34664336-E1206F6A-894C-4A81-813E-A957BB80A181 Q34726830-2C8ABEDC-FF74-4778-997F-D6E557638B82 Q34800913-3F7EEF08-8E85-467A-B220-55BF94C1D8E6 Q34958259-5F9FC652-5C7D-45BD-9F93-A1C2ED26DF73 Q34973749-E48EC08E-B41F-4473-AB73-3042D35B2475 Q34981297-9E533674-A5D5-4941-ACA7-4F2D6C342C03 Q35043143-35512DDE-8E20-4BDA-ADCF-ED637F5536CC Q35080513-E0FAAF13-C468-44DD-A5AB-08000B9960F9 Q35095540-321E380F-DC54-4EB0-B062-9115E47B684F Q35111227-A16A8E32-3F96-4233-B41F-F413107FF590 Q35177586-445D4800-D3D3-4E3F-BCA7-56771FF48C92 Q35181215-A500395A-D5DD-4990-9B6B-F16644EC9E53 Q35215102-261E15F2-FC29-48A5-B0AD-7E011A852833 Q35217395-B97EFEA2-311F-4EE0-91B4-2FD9144EBF66 Q35217467-32D52AD2-8A12-4458-8777-5751B77C86EE Q35555933-9740D3E2-F76B-486D-B754-CFDBD8DE0030 Q35576389-874BFD3D-8E13-4F56-91F2-2F1CAEDEADAF Q35708220-CE432CD1-67C1-42DE-B9B4-F8993556D189 Q35790757-8831AAFA-04E6-4B72-851A-1E5A98F7A444 Q35920339-461FE77C-A2C2-404C-BDE8-9EDE08BE9323 Q36012138-D2F7794A-FF86-49D6-8AFC-EFB138F0292B Q36056243-CE2B0933-E0D5-46E4-AC89-0F0AEC932E52 Q36110484-709C6E32-DBF4-4464-8034-C6F9F0BB218B Q36130821-242A181B-F51F-4A2A-AC6E-3130816BDEC1

P2860

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.

http://www.wikidata.org/entity/Q37391969

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 06 August 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Arginase inhibition restores N ...... ascular stiffness in old rats.

@en

Arginase inhibition restores N ...... ascular stiffness in old rats.

@nl

type

label

Arginase inhibition restores N ...... ascular stiffness in old rats.

@en

Arginase inhibition restores N ...... ascular stiffness in old rats.

@nl

prefLabel

Arginase inhibition restores N ...... ascular stiffness in old rats.

@en

Arginase inhibition restores N ...... ascular stiffness in old rats.

@nl

P1433

Q37391969-03CD06DC-EAF1-4680-91F2-70CF24DCAA61

P1476

Q37391969-2A229BB2-9CF7-469C-97E4-E442BA171DD7

P2093

Q37391969-09137F93-6F42-4F69-9558-9E6F33A1D01B

Q37391969-0CC71C9A-B7B7-4189-ADC2-2A38B946B34F

Q37391969-2DC14FD8-28A9-44E4-A84B-DF3C9678D752

Q37391969-30B09DA8-7236-42C8-BF2A-6D7CBC0F2B07

Q37391969-3AB9D49B-D584-4C68-B7CC-D1226913DCCE

Q37391969-5AFF6E69-C081-47B2-A27A-0181B4FF2CF8

Q37391969-65FF68E1-49A9-4F6C-997E-4B01619BB41A

Q37391969-6DE74EB1-0463-4B4B-A846-EF075F93E821

Q37391969-9012CFFD-36C8-42FB-9494-CC8569DA7558

Q37391969-9E16AA44-6F00-4738-81E5-AA9038F5002A

P2860

Q37391969-00B998DD-DA62-4788-8EB6-E3135ED03F3F

Q37391969-050E7762-0304-4032-A670-935A8EBDA0CE

Q37391969-094659F8-0211-4584-A717-0FB13B782CF0

Q37391969-0F00CF99-EDE9-4133-B2DB-8F727CD8D3CC

Q37391969-108BF282-CCD6-4DDF-8D15-C2D1B19D9F72

Q37391969-1E8D8660-1298-4715-A11E-618A15CC012E

Q37391969-21AC4FC8-1795-45CA-A448-4AE60A0A9B43

Q37391969-23D67EA4-35AF-47A8-9983-3B9455D63DA3

Q37391969-24F51AC1-AFC8-417D-82FB-96E0135D26F6

Q37391969-28778D1E-B4BD-4836-86CD-88A2121C967B

P304

Q37391969-446883F4-BCCB-4FFD-91BA-4E696F1E21FB

P31

Q37391969-78772F97-22EE-4BF6-978B-C8DE532C2140

P356

Q37391969-992E201B-8DA3-42C2-910E-8170617AF983

P407

Q37391969-F450B295-5A7C-4A8A-8510-707D1A94BF5B

P433

Q37391969-73F1D5A5-65C9-4236-8A13-AFB5989B446F

P478

Q37391969-FD769C81-8306-47E4-BB6C-2B65EFC322A3

P50

Q37391969-6E4ABEA9-3981-43CD-9137-DD0531F5A260

P577

Q37391969-67F3F585-449D-46C3-801C-932D7556124A

P5875

Q37391969-F7D1414B-04E9-457A-B259-0A28F237C2C9

P698

Q37391969-7F753A5F-2F82-412A-9882-3159DD3EE347

P921

Q37391969-2E46E44C-9CEE-4B59-B8EA-858270F50BDB

P932

Q37391969-60121CDF-C175-4A93-85CE-DF2D58344396

P356

JAPPLPHYSIOL.91393.2008

P1433

Journal of Applied Physiology

P1476

Arginase inhibition restores N ...... vascular stiffness in old rats

@en

P2093

Alanah Webb

http://www.w3.org/2001/XMLSchema#string

Andre Camara

http://www.w3.org/2001/XMLSchema#string

Artin A Shoukas

http://www.w3.org/2001/XMLSchema#string

Dan E Berkowitz

http://www.w3.org/2001/XMLSchema#string

Daniel Nyhan

http://www.w3.org/2001/XMLSchema#string

David W Christianson

http://www.w3.org/2001/XMLSchema#string

Gautam Sikka

http://www.w3.org/2001/XMLSchema#string

Hunter C Champion

http://www.w3.org/2001/XMLSchema#string

Jae Hyung Kim

http://www.w3.org/2001/XMLSchema#string

Kevin G Soucy

http://www.w3.org/2001/XMLSchema#string

P2860

Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2

Crystal structure of human arginase I at 1.29-A resolution and exploration of inhibition in the immune response.

Oxidants, oxidative stress and the biology of ageing

Endothelial nitric oxide synthase in vascular disease: from marvel to menace

Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction

Development of progressive aortic vasculopathy in a rat model of aging

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load.

Asymmetric dimethylarginine, derangements of the endothelial nitric oxide synthase pathway, and cardiovascular diseases.

P304

1249-1257

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1152/JAPPLPHYSIOL.91393.2008

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

107

http://www.w3.org/2001/XMLSchema#string

P50

P577

2009-08-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26723463

http://www.w3.org/2001/XMLSchema#string

P698

19661445

http://www.w3.org/2001/XMLSchema#string

P921

P932

2763842

http://www.w3.org/2001/XMLSchema#string