Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells.
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BLM protein mitigates formaldehyde-induced genomic instabilityInvestigation of bacterial nucleotide excision repair using single-molecule techniques.5-Hydroxy-5-methylhydantoin DNA lesion, a molecular trap for DNA glycosylasesWss1 metalloprotease partners with Cdc48/Doa1 in processing genotoxic SUMO conjugatesFunctional Toxicogenomic Profiling Expands Insight into Modulators of Formaldehyde Toxicity in YeastXPA impacts formation but not proteasome-sensitive repair of DNA-protein cross-links induced by chromateCrosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVAWidespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination.DNA-protein cross-linking by 1,2,3,4-diepoxybutane.S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediated cell death by formaldehyde.Mechlorethamine-induced DNA-protein cross-linking in human fibrosarcoma (HT1080) cells.The impact of FANCD2 deficiency on formaldehyde-induced toxicity in human lymphoblastoid cell lines.Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.The mTOR inhibitor rapamycin suppresses DNA double-strand break repairProteasome activity is important for replication recovery, CHK1 phosphorylation and prevention of G2 arrest after low-dose formaldehyde.Formaldehyde-induced genome instability is suppressed by an XPF-dependent pathway.T7 RNA polymerases backed up by covalently trapped proteins catalyze highly error prone transcriptionCovalent DNA-Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells5-aza-2'-deoxycytidine-induced genome rearrangements are mediated by DNMT1.Detection of DNA-protein crosslinks (DPCs) by novel direct fluorescence labeling methods: distinct stabilities of aldehyde and radiation-induced DPCs.An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells: NUCLEOTIDE EXCISION REPAIR, DNA DAMAGE CHECKPOINT, AND APOPTOSISATM and KAT5 safeguard replicating chromatin against formaldehyde damage.Translocation and stability of replicative DNA helicases upon encountering DNA-protein cross-links.DNA-reactive protein monoepoxides induce cell death and mutagenesis in mammalian cellsSynthesis of sequence-specific DNA-protein conjugates via a reductive amination strategy.Role of aldehydes in the toxic and mutagenic effects of nitrosamines.Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.4-Thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy.What is the DNA repair defect underlying Fanconi anemia?Mass Spectrometry Based Proteomics Study of Cisplatin-Induced DNA-Protein Cross-Linking in Human Fibrosarcoma (HT1080) Cells.Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins.A unique uracil-DNA binding protein of the uracil DNA glycosylase superfamily.Mechanisms of DNA-protein crosslink repair.Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei.Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells.The role of DNA damage and repair in decitabine-mediated apoptosis in multiple myeloma.Repair of a DNA-protein crosslink by replication-coupled proteolysis.Formation and repair of DNA-protein crosslink damage.A quantitative PCR-based assay reveals that nucleotide excision repair plays a predominant role in the removal of DNA-protein crosslinks from plasmids transfected into mammalian cells.Do chromosome changes in blood cells implicate formaldehyde as a leukemogen?
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Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Homologous recombination but n ...... ross-links in mammalian cells.
@en
Homologous recombination but n ...... ross-links in mammalian cells.
@nl
type
label
Homologous recombination but n ...... ross-links in mammalian cells.
@en
Homologous recombination but n ...... ross-links in mammalian cells.
@nl
prefLabel
Homologous recombination but n ...... ross-links in mammalian cells.
@en
Homologous recombination but n ...... ross-links in mammalian cells.
@nl
P2093
P2860
P356
P1476
Homologous recombination but n ...... ross-links in mammalian cells.
@en
P2093
Atsushi Katafuchi
Bennett Van Houten
Deborah L Croteau
Hiroaki Terato
Hiroshi Ide
Hiroshi Tauchi
Keisuke Makino
Kenta Iijima
Mayumi Matsubara
Seung Pil Pack
P2860
P304
27065-27076
P356
10.1074/JBC.M109.019174
P407
P577
2009-08-11T00:00:00Z