Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
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The structure of a protein primer-polymerase complex in the initiation of genome replication.NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU)Arbovirus high fidelity variant loses fitness in mosquitoes and micePicornavirus genome replication: roles of precursor proteins and rate-limiting steps in oriI-dependent VPg uridylylationThe crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerasesNMR structure of the viral peptide linked to the genome (VPg) of poliovirusStimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDproRNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory MechanismsPicornavirus RNA polyadenylation by 3D(pol), the viral RNA-dependent RNA polymeraseCommon and unique features of viral RNA-dependent polymerasesStructural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase.A second, non-canonical RNA-dependent RNA polymerase in SARS CoronavirusCrystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom ResolutionStabilization of Poliovirus Polymerase by NTP Binding and Fingers–Thumb InteractionsDe Novo Initiation of RNA Synthesis by the Arterivirus RNA-Dependent RNA PolymeraseStructure-function relationships among RNA-dependent RNA polymerasesAnalysis of Flavivirus NS5 Methyltransferase Cap BindingCrystal Structure of Poliovirus 3CD Protein: Virally Encoded Protease and Precursor to the RNA-Dependent RNA PolymeraseActivation mechanism of a noncanonical RNA-dependent RNA polymeraseCrystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus PolymerasesStructure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to RibavirinStructural basis for active site closure by the poliovirus RNA-dependent RNA polymeraseStructures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in ChinaCrystal Structure of the full-length Japanese encephalitis virus NS5 reveals a conserved methyltransferase-polymerase interfaceRNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation stateDistinct Conformations of a Putative Translocation Element in Poliovirus PolymeraseThe Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active SiteArsenic binding to proteinsThe RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus familyThe Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent PolymerasesA Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae FamilyPerturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongationStructural basis of viral RNA-dependent RNA polymerase catalysis and translocationQuasispecies diversity determines pathogenesis through cooperative interactions in a viral populationAttenuation of human enterovirus 71 high-replication-fidelity variants in AG129 miceEnzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays.UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replicationFidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds.Fidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus.Poliovirus proteins induce membrane association of GTPase ADP-ribosylation factor.
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Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 August 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Structural basis for proteolys ...... RNA-dependent RNA polymerase.
@en
Structural basis for proteolys ...... RNA-dependent RNA polymerase.
@nl
type
label
Structural basis for proteolys ...... RNA-dependent RNA polymerase.
@en
Structural basis for proteolys ...... RNA-dependent RNA polymerase.
@nl
prefLabel
Structural basis for proteolys ...... RNA-dependent RNA polymerase.
@en
Structural basis for proteolys ...... RNA-dependent RNA polymerase.
@nl
P2860
P356
P1433
P1476
Structural basis for proteolys ...... RNA-dependent RNA polymerase.
@en
P2093
Aaron A Thompson
Olve B Peersen
P2860
P304
P356
10.1038/SJ.EMBOJ.7600357
P407
P577
2004-08-12T00:00:00Z