Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.
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The Response to Oxidative DNA Damage in Neurons: Mechanisms and DiseaseExpansion, mosaicism and interruption: mechanisms of the CAG repeat mutation in spinocerebellar ataxia type 1Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3Transcription, epigenetics and ameliorative strategies in Huntington's Disease: a genome-wide perspectiveModifiers of (CAG)(n) instability in Machado-Joseph disease (MJD/SCA3) transmissions: an association study with DNA replication, repair and recombination genes.Heterozygosity for a hypomorphic Polβ mutation reduces the expansion frequency in a mouse model of the Fragile X-related disorders.The role of the mammalian DNA end-processing enzyme polynucleotide kinase 3'-phosphatase in spinocerebellar ataxia type 3 pathogenesis.Repeat instability during DNA repair: Insights from model systemsLarge expansion of CTG•CAG repeats is exacerbated by MutSβ in human cells.The Repeat Expansion Diseases: The dark side of DNA repair.DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseasesAbsence of MutSβ leads to the formation of slipped-DNA for CTG/CAG contractions at primate replication forks.RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair.A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)n Repeats Associated with Friedreich's AtaxiaThe Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae.
P2860
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P2860
Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.
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2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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name
Expression levels of DNA repli ...... ase protein expression or age.
@en
Expression levels of DNA repli ...... ase protein expression or age.
@nl
type
label
Expression levels of DNA repli ...... ase protein expression or age.
@en
Expression levels of DNA repli ...... ase protein expression or age.
@nl
prefLabel
Expression levels of DNA repli ...... ase protein expression or age.
@en
Expression levels of DNA repli ...... ase protein expression or age.
@nl
P2093
P2860
P356
P1476
Expression levels of DNA repli ...... ase protein expression or age.
@en
P2093
Albert R La Spada
Amanda G Mason
Christopher E Pearson
Jodie P Simard
Randell T Libby
Richard P Beyer
Stephanie Tomé
Theodor K Bammler
P2860
P304
P356
10.1093/HMG/DDT551
P577
2013-11-03T00:00:00Z