Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
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The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factorsMouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathwayDissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domainp95vav associates with the nuclear protein Ku-70STAT3 inhibitors for cancer therapy: Have all roads been explored?Signal transducer and activator of transcription 5A/B in prostate and breast cancersSTAT signaling in the pathogenesis and treatment of cancerErythropoietin and Friend virus gp55 activate different JAK/STAT pathways through the erythropoietin receptor in erythroid cellsInvolvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell lineTranscriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells.Dichotomy between factors inducing the immunosuppressive enzyme IL-4-induced gene 1 (IL4I1) in B lymphocytes and mononuclear phagocytesEnhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5.STAT5 and Oct-1 form a stable complex that modulates cyclin D1 expression.Enu mutagenesis identifies a novel platelet phenotype in a loss-of-function Jak2 allele.Transcription factor Stat5a/b as a therapeutic target protein for prostate cancer.A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.Identification of tyrosine residues within the intracellular domain of the erythropoietin receptor crucial for STAT5 activationErythropoietin-induced erythroid differentiation of the human erythroleukemia cell line TF-1 correlates with impaired STAT5 activationTyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiationAbsence of cytokine receptor-dependent specificity in red blood cell differentiation in vivoErythropoietin induces activation of Stat5 through association with specific tyrosines on the receptor that are not required for a mitogenic response.Functional regions of the mouse thrombopoietin receptor cytoplasmic domain: evidence for a critical region which is involved in differentiation and can be complemented by erythropoietinDeletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.Naturally occurring dominant negative variants of Stat5.Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha geneControl of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway.Different mutations of the human c-mpl gene indicate distinct haematopoietic diseasesInterleukin 2 plays a central role in Th2 differentiation.New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation.Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.Thrombopoietin in normal and neoplastic stem cell development.STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells.Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway.Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo.Regulation of polymorphonuclear cell activation by thrombopoietin.Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5Specific DNA binding of Stat5, but not of glucocorticoid receptor, is required for their functional cooperation in the regulation of gene transcription.Unique signal transduction of Eyk: constitutive stimulation of the JAK-STAT pathway by an oncogenic receptor-type tyrosine kinase.The rapid inactivation of nuclear tyrosine phosphorylated Stat1 depends upon a protein tyrosine phosphatase.
P2860
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P2860
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 1995
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
@en
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
@nl
type
label
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
@en
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
@nl
prefLabel
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
@en
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
@nl
P2093
P2860
P1433
P1476
Thrombopoietin activates a STAT5-like factor in hematopoietic cells.
@en
P2093
Dusanter-Fourt I
Gisselbrecht S
Gouilleux F
P2860
P304
P407
P577
1995-06-01T00:00:00Z