The Human Glioma-Associated Oncogene Homolog 1 (GLI1) Family of Transcription Factors in Gene Regulation and Diseases.
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Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and ChemoresistanceThe Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human CancerSubgroup-specific alternative splicing in medulloblastomaGli1 contributes to cellular resistance to cisplatin through altered cellular accumulation of the drug.Clinicopathological correlation and prognostic significance of sonic hedgehog protein overexpression in human gastric cancerUpregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.Gli regulates MUC5AC transcription in human gastrointestinal cellsMicroRNA-602 and microRNA-608 regulate sonic hedgehog expression via target sites in the coding region in human chondrocytesImpact of Sonic Hedgehog Pathway Expression on Outcome in HPV Negative Head and Neck Carcinoma Patients after Surgery and Adjuvant RadiotherapyHedgehog controls hepatic stellate cell fate by regulating metabolismResponse to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth.GLI1 upregulates C-JUN through a specific 130-kDa isoformAberrant activation of hedgehog signaling promotes cell proliferation via the transcriptional activation of forkhead Box M1 in colorectal cancer cells.Targeting Ras-RAF-ERK and its interactive pathways as a novel therapy for malignant gliomas.Hedgehog signaling: networking to nurture a promalignant tumor microenvironment.Hedgehog signalling in gut development, physiology and cancer.Hedgehog pathway and GLI1 isoforms in human cancer.Mechanisms regulating glioma invasion.Transcription factor glioma-associated oncogene homolog 1 is required for transforming growth factor-β1-induced epithelial-mesenchymal transition of non-small cell lung cancer cells.Plasma membrane wounding and repair in pulmonary diseases.Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing.Identification, functional characterization, and pathobiological significance of GLI1 isoforms in human cancers.Targeting GLI proteins in human cancer by small molecules (WO2014116651 A1): a patent evaluation.NPM-ALK: The Prototypic Member of a Family of Oncogenic Fusion Tyrosine Kinases.The role of KPNβ1 in neuro-oncology.Oncogenic Functions of Gli1 in Pancreatic Adenocarcinoma Are Supported by Its PRMT1-Mediated Methylation.Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells.Disruption of the Hedgehog signaling pathway in inflammatory bowel disease fosters chronic intestinal inflammation.Interaction between STAT3 and GLI1/tGLI1 oncogenic transcription factors promotes the aggressiveness of triple-negative breast cancers and HER2-enriched breast cancer.Comparative genomic analysis of intracranial germ cell tumors - the preliminary study focused on Sonic Hedgehog signaling pathway.
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The Human Glioma-Associated Oncogene Homolog 1 (GLI1) Family of Transcription Factors in Gene Regulation and Diseases.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on June 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The Human Glioma-Associated On ...... Gene Regulation and Diseases.
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The Human Glioma-Associated Oncogene Homolog 1
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type
label
The Human Glioma-Associated On ...... Gene Regulation and Diseases.
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The Human Glioma-Associated Oncogene Homolog 1
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prefLabel
The Human Glioma-Associated On ...... Gene Regulation and Diseases.
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The Human Glioma-Associated Oncogene Homolog 1
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P1433
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The Human Glioma-Associated On ...... Gene Regulation and Diseases.
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P2860
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P356
10.2174/138920210791233108
P50
P577
2010-06-01T00:00:00Z