Sorting nexins provide diversity for retromer-dependent trafficking events. - Test2 - elhamkhani - TriplyDB

Sorting nexins provide diversity for retromer-dependent trafficking events.

Sorting nexins provide diversity for retromer-dependent trafficking events.

http://www.wikidata.org/entity/Q37970882

about

Nanotechnology: toxicologic pathology VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface FAM65B is a membrane-associated protein of hair cell stereocilia required for hearing.Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A The EHEC-host interactome reveals novel targets for the translocated intimin receptor A mechanism for retromer endosomal coat complex assembly with cargo Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination EARP is a multisubunit tethering complex involved in endocytic recycling Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease Multiple Roles of the Small GTPase Rab7 Role of the Retromer Complex in Neurodegenerative Diseases The retromer complex - endosomal protein recycling and beyond Phosphoinositides: tiny lipids with giant impact on cell regulation Membrane curvature at a glance PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes.The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration Identification of SH3 domain proteins interacting with the cytoplasmic tail of the a disintegrin and metalloprotease 10 (ADAM10)Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism.Copper directs ATP7B to the apical domain of hepatic cells via basolateral endosomes Biogenesis of endosome-derived transport carriers.Structure of human SNX10 reveals insights into its role in human autosomal recessive osteopetrosis Evidence for a Golgi-to-endosome protein sorting pathway in Plasmodium falciparum Cell surface recycling in yeast: mechanisms and machineries Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control Retromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in Drosophila Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function Snx3 regulates recycling of the transferrin receptor and iron assimilation EFA6A, a guanine nucleotide exchange factor for Arf6, interacts with sorting nexin-1 and regulates neurite outgrowth CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL Depletion or over-expression of Sh3px1 results in dramatic changes in cell morphology.Microtubule motors mediate endosomal sorting by maintaining functional domain organization SNX15 links clathrin endocytosis to the PtdIns3P early endosome independently of the APPL1 endosome.The multivesicular body is the major internal site of prion conversion.A CDC25 family protein phosphatase gates cargo recognition by the Vps26 retromer subunit.VPS35, the Retromer Complex and Parkinson's Disease.Pharmacological chaperones stabilize retromer to limit APP processing.Comparative gene identification 58/α/β hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity

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P2860

Sorting nexins provide diversity for retromer-dependent trafficking events.

http://www.wikidata.org/entity/Q37970882

description

article científic

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article scientifique

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articol științific

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articolo scientifico

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artigo científico

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artigo científico

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artigo científico

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artikel ilmiah

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artikull shkencor

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artículo científico

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name

Sorting nexins provide diversity for retromer-dependent trafficking events.

@en

Sorting nexins provide diversity for retromer-dependent trafficking events.

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type

label

Sorting nexins provide diversity for retromer-dependent trafficking events.

@en

Sorting nexins provide diversity for retromer-dependent trafficking events.

@nl

prefLabel

Sorting nexins provide diversity for retromer-dependent trafficking events.

@en

Sorting nexins provide diversity for retromer-dependent trafficking events.

@nl

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Nature Cell Biology

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Sorting nexins provide diversity for retromer-dependent trafficking events.

@en

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Hendrik C Korswagen

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Peter J Cullen

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P2860

SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

The PX-BAR membrane-remodeling unit of sorting nexin 9

The mammalian retromer regulates transcytosis of the polymeric immunoglobulin receptor

Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1

SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment

The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport.

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor

SNX1 defines an early endosomal recycling exit for sortilin and mannose 6-phosphate receptors

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29-37

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scholarly article

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10.1038/NCB2374

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1

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14

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2011-12-22T00:00:00Z

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51919377

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1014903907

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22193161

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retromer, tubulation complex

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3613977

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