Cyclotides as grafting frameworks for protein engineering and drug design applications.
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Advanced Developments in Cyclic Polymers: Synthesis, Applications, and PerspectivesAnticancer and toxic properties of cyclotides are dependent on phosphatidylethanolamine phospholipid targetingRacemic and quasi-racemic X-ray structures of cyclic disulfide-rich peptide drug scaffoldsComputational Design of Hypothetical New Peptides Based on a Cyclotide Scaffold as HIV gp120 InhibitorClustering of disulfide-rich peptides provides scaffolds for hit discovery by phage display: application to interleukin-23Peptides, Peptidomimetics, and Polypeptides from Marine Sources: A Wealth of Natural Sources for Pharmaceutical Applications.Peptides and peptidomimetics as immunomodulators.Dynamic scenario of membrane binding process of kalata b1Optimization of the cyclotide framework to improve cell penetration properties.The evolution of Momordica cyclic peptides.Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum.Cystine-knot peptides targeting cancer-relevant human cytotoxic T lymphocyte-associated antigen 4 (CTLA-4).Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration.Cyclotide discovery in Gentianales revisited--identification and characterization of cyclic cystine-knot peptides and their phylogenetic distribution in Rubiaceae plants.Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy.Joseph Rudinger memorial lecture: discovery and applications of cyclotides.Review cyclic peptides on a merry-go-round; towards drug design.Chlorotoxin: Structure, activity, and potential uses in cancer therapy.Rational, computer-enabled peptide drug design: principles, methods, applications and future directions.Structure-Activity Relationships of Insect Defensins.Novel approaches to the design of bioavailable melanotropins.Host defense peptide-derived privileged scaffolds for anti-infective drug discovery.Constrained Cyclic Peptides as Immunomodulatory Inhibitors of the CD2:CD58 Protein-Protein Interaction.Plant cystine-knot peptides: pharmacological perspectives.Unveiling the diversity of cyclotides by combining peptidome and transcriptome analysis.Discovery, structure, function, and applications of cyclotides: circular proteins from plants.Orientation and Location of the Cyclotide Kalata B1 in Lipid Bilayers Revealed by Solid-State NMR.Design of cyclized selective melanotropins.Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides.Two Blast-independent tools, CyPerl and CyExcel, for harvesting hundreds of novel cyclotides and analogues from plant genomes and protein databases.Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase.Co-expression of a cyclizing asparaginyl endopeptidase enables efficient production of cyclic peptides in planta.Computational Studies of Snake Venom Toxins.Structural basis of ribosomal peptide macrocyclization in plants.Intramolecular Thioether Crosslinking to Increase the Proteolytic Stability of Affibody Molecules.Biodistribution of the cyclotide MCoTI-II, a cyclic disulfide-rich peptide drug scaffold.Influence of material stretchability on the equilibrium shape of a Möbius band.Pinpointing disulfide connectivities in cysteine-rich proteins.Synthetic Cystine-Knot Miniproteins - Valuable Scaffolds for Polypeptide Engineering.Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.
P2860
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P2860
Cyclotides as grafting frameworks for protein engineering and drug design applications.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
Cyclotides as grafting frameworks for protein engineering and drug design applications.
@en
type
label
Cyclotides as grafting frameworks for protein engineering and drug design applications.
@en
prefLabel
Cyclotides as grafting frameworks for protein engineering and drug design applications.
@en
P2860
P50
P356
P1433
P1476
Cyclotides as grafting frameworks for protein engineering and drug design applications
@en
P2093
Aaron G Poth
Lai Y Chan
P2860
P304
P356
10.1002/BIP.22284
P577
2013-09-01T00:00:00Z