BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
about
Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombinationHuman exonuclease 5 is a novel sliding exonuclease required for genome stabilityBiochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replicationScaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repairDNA End Resection: Facts and MechanismsInterplay between Fanconi anemia and homologous recombination pathways in genome integrityATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to AdaptorHsp90: A New Player in DNA Repair?Nucleases in homologous recombination as targets for cancer therapyModulation of DNA damage and repair pathways by human tumour virusesDisease-causing missense mutations in human DNA helicase disordersThe role of RecQ helicases in non-homologous end-joiningDouble-strand break repair on sex chromosomes: challenges during male meiotic prophaseDNA double-strand break repair pathway choice and cancerTOPping off meiosisSources of DNA double-strand breaks and models of recombinational DNA repairRepair of strand breaks by homologous recombinationSingle-molecule visualization of RecQ helicase reveals DNA melting, nucleation, and assembly are required for processive DNA unwinding.Emerging critical roles of Fe-S clusters in DNA replication and repair.BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51.Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repairThe Structural Basis for Substrate Recognition by Mammalian Polynucleotide Kinase 3′ PhosphataseInsights into Chi recognition from the structure of an AddAB-type helicase-nuclease complexDNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease ActivitiesEnd-resection at DNA double-strand breaks in the three domains of lifeNuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity.Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation.Envisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairA Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous RecombinationMammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrityEXD2 promotes homologous recombination by facilitating DNA end resectionBRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous RecombinationMCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complexMicrohomology-mediated end joining: new players join the teamAssociation of BLM and BRCA1 during Telomere Maintenance in ALT CellsSUMO-targeted ubiquitin E3 ligase RNF4 is required for the response of human cells to DNA damageThe HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanismSae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling.
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P2860
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@ast
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@en
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@en-gb
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@nl
type
label
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@ast
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@en
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@en-gb
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@nl
prefLabel
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@ast
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@en
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@en-gb
BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@nl
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BLM-DNA2-RPA-MRN and EXO1-BLM- ...... ies for human DNA break repair
@en
P2093
Amitabh V Nimonkar
Claire Wyman
Eri Kinoshita
Jochen Genschel
Judith L Campbell
Paul Modrich
Piotr Polaczek
Stephen C Kowalczykowski
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P304
P3181
P356
10.1101/GAD.2003811
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P577
2011-02-15T00:00:00Z