tumor suppressor p53 binds with high affinity to CTG.CAG trinucleotide repeats and induces topological alterations in mismatched duplexes.
about
Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.p53 Specifically Binds Triplex DNA In Vitro and in CellsThe versatile interactions of p53 with DNA: when flexibility serves specificity.p53 and disease: when the guardian angel fails.Interactions of mutant p53 with DNA: guilt by association.Functional analysis of p53 binding under differential stresses.Recognition of Local DNA Structures by p53 Protein.Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity.A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells.Wild-type p53 binds to MYC promoter G-quadruplex.
P2860
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P2860
tumor suppressor p53 binds with high affinity to CTG.CAG trinucleotide repeats and induces topological alterations in mismatched duplexes.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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2005年學術文章
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2005年學術文章
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name
tumor suppressor p53 binds wit ...... ations in mismatched duplexes.
@en
type
label
tumor suppressor p53 binds wit ...... ations in mismatched duplexes.
@en
prefLabel
tumor suppressor p53 binds wit ...... ations in mismatched duplexes.
@en
P2093
P2860
P356
P1476
tumor suppressor p53 binds wit ...... ations in mismatched duplexes.
@en
P2093
Gabriele Warnecke
Korden Walter
Wolfgang Deppert
P2860
P304
42497-42507
P356
10.1074/JBC.M507038200
P407
P577
2005-10-17T00:00:00Z