about
Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3aThe developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell developmentDown-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activatorAn early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryoData integration in the era of omics: current and future challengesChromatin signatures of pluripotent cell linesCohesins functionally associate with CTCF on mammalian chromosome armsThe tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangementHeterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locusPI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factorsBone progenitor dysfunction induces myelodysplasia and secondary leukaemia.microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.A role for Dicer in immune regulationCohesin at active genes: a unifying theme for cohesin and gene expression from model organisms to humans.Using heterokaryons to understand pluripotency and reprogrammingA role for cohesin in T-cell-receptor rearrangement and thymocyte differentiationmicroRNAs regulate cell-to-cell variability of endogenous target gene expression in developing mouse thymocytes.Upstream of Ikaros.Sensory adaptation in naive peripheral CD4 T cells.Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice.Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.DNA synthesis is required for reprogramming mediated by stem cell fusionDifferent roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.Long-range regulation of cytokine gene expression.Dicer-dependent pathways regulate chondrocyte proliferation and differentiationMicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells.A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.RNAi and chromatin in T cell development and function.Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming.Condensin goes with the family but not with the flowCohesin-based chromatin interactions enable regulated gene expression within preexisting architectural compartments.Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes.The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes.Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.Cohesin: a global player in chromosome biology with local ties to gene regulation.Ikaros in immune receptor signaling, lymphocyte differentiation, and function.Cohesin and chromatin organisation.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Matthias Merkenschlager
@ast
Matthias Merkenschlager
@en
Matthias Merkenschlager
@es
Matthias Merkenschlager
@pt
Matthias Merkenschlager
@sl
type
label
Matthias Merkenschlager
@ast
Matthias Merkenschlager
@en
Matthias Merkenschlager
@es
Matthias Merkenschlager
@pt
Matthias Merkenschlager
@sl
prefLabel
Matthias Merkenschlager
@ast
Matthias Merkenschlager
@en
Matthias Merkenschlager
@es
Matthias Merkenschlager
@pt
Matthias Merkenschlager
@sl
P106
P21
P31
P496
0000-0003-2889-3288