Dicer-dependent pathways regulate chondrocyte proliferation and differentiation
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MicroRNA-221 regulates chondrogenic differentiation through promoting proteosomal degradation of slug by targeting Mdm2A microRNA signature for a BMP2-induced osteoblast lineage commitment programmiR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1Roles of microRNAs in prenatal chondrogenesis, postnatal chondrogenesis and cartilage-related diseasesDicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defectsRoles of microRNA and signaling pathway in osteoarthritis pathogenesisCurrent Status and Strategy of microRNA Research for Cartilage Development and Osteoarthritis PathogenesisMicroRNAs regulate bone development and regenerationBone marrow stroma-derived miRNAs as regulators, biomarkers and therapeutic targets of bone metastasisMatrix-embedded cells control osteoclast formationBMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formationmiR-1247 functions by targeting cartilage transcription factor SOX9The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal archDeletion of Dicer in somatic cells of the female reproductive tract causes sterility.Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes.MicroRNA-145 regulates chondrogenic differentiation of mesenchymal stem cells by targeting Sox9.Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs.MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responsesLoss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failureMicroRNAs and micromanaging the skeleton in disease, development and evolutionAltered expression of circulating microRNA in plasma of patients with primary osteoarthritis and in silico analysis of their pathwaysDicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes.p16INK4a and its regulator miR-24 link senescence and chondrocyte terminal differentiation-associated matrix remodeling in osteoarthritis.miR-146a facilitates osteoarthritis by regulating cartilage homeostasis via targeting Camk2d and Ppp3r2Upregulation of miR-23b enhances the autologous therapeutic potential for degenerative arthritis by targeting PRKACB in synovial fluid-derived mesenchymal stem cells from patients.MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.Targeted deletion of Capn4 in cells of the chondrocyte lineage impairs chondrocyte proliferation and differentiationMicroRNA-140 plays dual roles in both cartilage development and homeostasis.MicroRNAs dynamically remodel gastrointestinal smooth muscle cellsDicer ablation in oligodendrocytes provokes neuronal impairment in miceMicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.Dicer activity in neural crest cells is essential for craniofacial organogenesis and pharyngeal arch artery morphogenesis.Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes.MicroRNA-1 regulates chondrocyte phenotype by repressing histone deacetylase 4 during growth plate development.miRNAs in circulation: mirroring bone conditions?MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4.The expression and function of microRNAs in chondrogenesis and osteoarthritis.Next-generation sequencing identifies equine cartilage and subchondral bone miRNAs and suggests their involvement in osteochondrosis physiopathology.
P2860
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P2860
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation
@en
type
label
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation
@en
prefLabel
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation
@en
P2093
P2860
P356
P1476
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation
@en
P2093
Andrew P McMahon
Bradley S Cobb
Ernestina Schipani
Henry M Kronenberg
Stephen J Rodda
P2860
P304
P356
10.1073/PNAS.0707900105
P407
P577
2008-01-31T00:00:00Z