Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.
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Erythropoietin Pathway: A Potential Target for the Treatment of DepressionMitochondrial Transcription Factor A and Mitochondrial Genome as Molecular Targets for Cisplatin-Based Cancer ChemotherapyB1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB.High BIM mRNA levels are associated with longer survival in advanced gastric cancerIndole phytoalexin derivatives induce mitochondrial-mediated apoptosis in human colorectal carcinoma cells.Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factorsDifferentiating responses of lung cancer cell lines to Doxorubicin exposure: in vitro Raman micro spectroscopy, oxidative stress and bcl-2 protein expression.Oral microbe-host interactions: influence of β-glucans on gene expression of inflammatory cytokines and metabolome profile.Role of Bcl-2 and its associated miRNAs in vasculogenic mimicry of hepatocellular carcinoma.Expression of Apoptosis-regulating Proteins Bcl-2 and Bax in Lymph Node Aspirates from Dogs with Lymphoma.CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses.Obatoclax, a Pan-BCL-2 Inhibitor, Targets Cyclin D1 for Degradation to Induce Antiproliferation in Human Colorectal Carcinoma Cells.Resistance to Cell Death and Its Modulation in Cancer Stem Cells.Matrine induces the apoptosis of fibroblast-like synoviocytes derived from rats with collagen-induced arthritis by suppressing the activation of the JAK/STAT signaling pathway.Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α (PGC-1α) Regulates the Expression of B-Cell Lymphoma/Leukemia-2 (Bcl-2) and Promotes the Survival of Mesenchymal Stem Cells (MSCs) via PGC-1α/ERRα Interaction in the Absence of Serum, HypoxBCL2 Regulation According to Molecular Subtype of Breast Cancer by Analysis of The Cancer Genome Atlas Database.Inhibition of paclitaxel resistance and apoptosis induction by cucurbitacin B in ovarian carcinoma cells.Non-canonical roles of Bcl-2 and Bcl-xL proteins: relevance of BH4 domain.Sec6/8 regulates Bcl-2 and Mcl-1, but not Bcl-xl, in malignant peripheral nerve sheath tumor cells.Synergistic killing of human small cell lung cancer cells by the Bcl-2-inositol 1,4,5-trisphosphate receptor disruptor BIRD-2 and the BH3-mimetic ABT-263.Attenuation of liver cancer development by oral glycerol supplementation in the rat.Microtubule destabilising agents: far more than just antimitotic anticancer drugs.Diverse Functions and Signal Transduction of the Exocyst Complex in Tumor Cells.Silencing of CDK2, but not CDK1, separates mitogenic from anti-apoptotic signaling, sensitizing p53 defective cells for synthetic lethality.Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size.Maintenance of the HIV Reservoir Is Antagonized by Selective BCL2 Inhibition.Effect of cAMP signaling on expression of glucocorticoid receptor, Bim and Bad in glucocorticoid-sensitive and resistant leukemic and multiple myeloma cells.Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo.Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax.Chromium IV exposure, via Src/Ras signaling, promotes cell transformation.The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1.The BCL-2 arbiters of apoptosis and their growing role as cancer targets.Caspase cleavage of Mcl-1 impairs its anti-apoptotic activity and proteasomal degradation in non-small lung cancer cells.The ratio of thioredoxin/Keap1 protein level is a predictor of distant metastasis in colorectal cancer.Molecular Cell Biology of Apoptosis and Necroptosis in Cancer.Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo.Lentivirus‑mediated MDA7/IL24 expression inhibits the proliferation of hepatocellular carcinoma cells.The impact of phosphatases on proliferative and survival signaling in cancer.
P2860
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P2860
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Emerging understanding of Bcl- ...... tic progression and treatment.
@en
type
label
Emerging understanding of Bcl- ...... tic progression and treatment.
@en
prefLabel
Emerging understanding of Bcl- ...... tic progression and treatment.
@en
P2093
P2860
P1476
Emerging understanding of Bcl- ...... stic progression and treatment
@en
P2093
Cristina Correia
Grzegorz S Nowakowski
Husheng Ding
Katherine L B Knorr
Nicole D Vincelette
Sun-Hee Lee
X Wei Meng
P2860
P304
P356
10.1016/J.BBAMCR.2015.03.012
P407
P577
2015-03-27T00:00:00Z