Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma.

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Inhibition of the spindle assembly checkpoint kinase Mps-1 as a novel therapeutic strategy in malignant mesothelioma.

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

@yue

2017年論文

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2017年論文

@zh-hk

2017年論文

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2017年論文

@zh-tw

2017年论文

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2017年论文

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2017年论文

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Inhibition of the spindle asse ...... egy in malignant mesothelioma.

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Inhibition of the spindle asse ...... egy in malignant mesothelioma.

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prefLabel

Inhibition of the spindle asse ...... egy in malignant mesothelioma.

@en

P1476

Inhibition of the spindle asse ...... tegy in malignant mesothelioma

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P2093

A Szymiczek

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H Yang

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I Pagano

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J M Mason

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M Carbone

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M Minaai

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M R Bray

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M Tanji

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S Pastorino

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T W Mak

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P2860

Evaluation of clonal origin of malignant mesothelioma

High incidence of somatic BAP1 alterations in sporadic malignant mesothelioma

Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignment

Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression

Germline BAP1 mutations predispose to malignant mesothelioma

Human malignant mesothelioma is recapitulated in immunocompetent BALB/c mice injected with murine AB cells.

Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function

Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase

A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

P2888

onc.2017.266

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6501-6507

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P31

scholarly article

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10.1038/ONC.2017.266

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English

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Andrea Napolitano

Harvey I Pass

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2017-07-31T00:00:00Z

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P6179

1090929515

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28759042

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5690838

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